Human hcxä Growth Hormone

Product Code: 3007B
Pack Size: 2 ug
Form: human recombinant protein
Product Type: Protein

Supplier: Symansis
Product Category: Cytokines / Growth Factors > Cytokine/Growth Factors

Further information: Symansis is the only company offering a large range of human cell expressed (hcx) recombinant proteins for life science researchers. Human cell expressed (hcx) recombinant human proteins have human post-translational modifications that can affect immunogenicity and stability. Human growth hormone (hGH) is a hormone that is required for normal human growth and development. It regulates an extensive variety of physiological functions relating to human growth and metabolism, primarily by inducing the expression of insulin-like growth factor 1 (IGF-1).The effects of hGH activity include the growth of bone, cartilage, and soft tissues, which occurs maximally during puberty. A deficiency of hGH or a lack of hGHR activation results in short stature while excessive hGH causes acromegaly. Recombinant hGH has been used clinically to treat hGH deficiency or other types of conditions that involve shortness, including Turner Syndrome. Circulating GH shows a great heterogeneity due to alternative splicing, differential posttranslational modifications of monomeric forms, oligomerization, optional binding to 2 different GH-binding proteins, and potentially proteolytic processing.

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