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iCell® Cardiomyocytes2 are cardiac myocytes derived from human induced pluripotent stem cells (iPSC). These cardiomyocytes, which are an extension of the well-characterized iCell product line, have been optimized for faster recovery from cryopreservation and can be used in a myriad of functional applications. The recent article by Block et al. in Scientific Reports indicates that iCell Cardiomyocytes2 have enhanced functional and structural benefits following culture on CELLvo™ Matrix Plus plates for seven days. This application protocol was produced by FUJUFILM Cellular Dynamics, Inc. and details the steps for plating iCell Cardiomyocytes2 on the CELLvo™ Matrix Plus plates
Documents
Cell Culture
StemBioSys
The CELLvoâ„¢ ChondroMatrix is an Extracellular Matrix (ECM) synthesized in vitro by human articular chondrocytes. This product is composed of proteins that were secreted and assembled by human articular chondrocytes during the production of the matrix.
Documents
Cell Culture
StemBioSys
Despite overwhelming evidence demonstrating the important role of the extracellular matrix in regulating cell behavior, traditional cell culture strategies do little to recreate a natural microenvironment. Presently, standard culture conditions inevitably lead to phenotypic drift, spontaneous differentiation, replicative senescence, and aberrant phenotypes that are unlike those found in the body. This may lead to experimental artifact in basic research or suboptimal clinical outcomes in translational research. To address this challenge, we focused our efforts on developing in vitro culture substrates that closely mimic natural microenvironments. Here we describe the development of scale-able, tissue-specific, cell-derived extracellular matrices for cell culture, and their applications in basic and translation research.
Videos
Cell Culture
StemBioSys
Despite overwhelming evidence demonstrating the important role of the extracellular matrix in regulating cell behavior, traditional cell culture strategies do little to recreate a natural microenvironment. Presently, standard culture conditions inevitably lead to phenotypic drift, spontaneous differentiation, replicative senescence, and aberrant phenotypes that are unlike those found in the body. This may lead to experimental artifact in basic research or suboptimal clinical outcomes in translational research. To address this challenge, we focused our efforts on developing in vitro culture substrates that closely mimic natural microenvironments. Here we describe the development of scale-able, tissue-specific, cell-derived extracellular matrices for cell culture, and their applications in basic and translation research.
Documents
Cell Culture
StemBioSys
hAD-MSCs are multipotent stem cells, capable of rapid proliferation, trilineage differentiation, and potent immunomodulation, found in abundance in the stromal vascular fraction of adipose tissue. Currently, adipose tissue is the most common source of MSCs in clinical use.
Documents
Cell Culture
StemBioSys
Human Articular Chondrocytes (HC-a) are mature cells responsible for elaborating and maintaining cartilage matrices in vivo. These cells can be difficult to isolate and expand, but have huge potential in translational research. CELLvoâ„¢ Chondrocytes are isolated from cadaveric articular cartilage of otherwise healthy donors in xeno-free conditions. When grown on the CELLvoâ„¢ Matrix, CELLvoâ„¢ HCs behave more naturally, allowing researchers greater control of their study.
Documents
Cell Culture
StemBioSys
The benefits of the unique CELLvo Matrix, the only natural cell culture substrate, will be discussed. The webinar describes the current challenges in removing cells from their native tissue and culturing them in a completely foreign environment such as tissue culture plastic. CELLvo Matrix addresses this by providing a 'home' that mimics the native cell derived micro-environment that they came from. It promotes cell adhesion with better isolation and proliferation of primary cells and enhanced cellular responsiveness to experimental variables.
Videos
Cell Culture
StemBioSys
MORE CELLS. SMALLER CELLS. HIGHER SSEA-4 EXPRESSION. StemBioSys’ naturally produced BM-HPME® allows for rapid and efficient expansion of stem cells which express biochemical and functional characteristics indicative of potent cells and a gene expression profile highlighted by increased expression of anti-inflammatory cytokines.
Documents
Cell Culture
StemBioSys
BM-HPME is an extracellular matrix (ECM) of proteins synthesized in vitro by bone marrow stromal cells. This product is composed of more than 150 proteins that were secreted and assembled by bone marrow cells during the production the HPME
Documents
Cell Culture
StemBioSys
TECHNICAL BULLETIN: Optimized Isolation and Growth of Mesenchymal Stem Cells The CELLvo™ Matrix Advantage
Documents
Cell Culture
StemBioSys
TECHNICAL BULLETIN: Optimized Isolation and Growth of Mesenchymal Stem Cells The CELLvo™ Matrix Advantage
Documents
Cell Culture
StemBioSys
Technical Bulletin: CELLvo� Human Cord Blood-Endothelial Progenitor Cells are Highly Proliferative and Angiogenic
Documents
Cell Culture
StemBioSys
StemBioSys® is committed to enhancing the quality and economics of isolating, growing and delivering stem cells through our novel High Performance Micro Environment (HPME®) technology. Our patented bone marrow HPME (BM-HPME®) creates a natural, protein based environment for expanding stem cells, resulting in small, proliferative and undifferentiated cells.
Documents
Cell Culture
StemBioSys
With superior colony forming abilities, greater vessel formation, and greater angiogenic potential in vitro as well as in vivo – as compared to hUVECs – CELLvo™ hCB-EPCs are the cell of choice for researchers wanting greater control of their tissue engineering studies.
Documents
Cell Culture
StemBioSys