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Service Documents by Abnova Corporation containing antib

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Abnova provides integrated Antibody LNP Conjugation Services to support research and preclinical development programs. Their capabilities include the use of customer-provided or Abnova-generated antibodies, LNP formulation development, and conjugation strategy optimisation. Leveraging expertise in antibodies, RNA technologies, and nanoparticle development, we deliver customised solutions tailored to diverse research and therapeutic applications.
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Abnova Corporation
Abnova provides a nanoCAR-T mRNA service that advances CAR-T cell therapy by integrating its NanoAb™ VHH antibody platform, mRNA IVT technology, and lipid nanoparticle (LNP) delivery. This approach allows precise ex vivo delivery of CAR instructions to T cells via mRNA encapsulated in ionizable lipid nanoparticles.
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Abnova Corporation
Abnovas VHH nanoBiTE™ service focuses on developing bispecific VHH antibodies without an Fc domain, ideal for immune and tumor cell redirecting, multiple epitope targeting, and novel immuno-oncology research. Their smaller molecular size enhances tissue penetration, making them suitable for hard-to-access areas like the tumor microenvironment. The absence of an Fc region prevents unwanted immune activation by avoiding Fc receptor binding, supporting precise mechanistic action. Engineered through the genetic fusion of two VHH domains via a flexible peptide linker, VHH nanoBiTE™ ensures robust antigen binding with reduced production complexity.
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Abnova Corporation
Abnova offers the NanoAb™ service for the production of target-specific VHH antibodies from the camelid VHH library.
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Abnova Corporation
Integration is the solution to deciphering the complexity of biology. The core of Abnovas integration is the generation and availability of antibodies and proteins targeting the human genome. These invaluable bio-tools are combined and utilised in a comprehensive repertoire of qualitative, quantitative, multiplexing, high throughput, and profiling applications to address the needs of research and discovery. Abnova has successfully developed and implemented these integrated solutions for the research community and industry.
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Abnova Corporation
Abnova offers high quality, efficient and cost-saving conjugation services, bridging antibody and fluorescent dyes, phycobiliproteins, streptavidin, biotin and enzymes. Since every antibody has its own unique characteristics, conjugation needs to be optimised. 0.2mg of total antibody of interest will be tested and analysed prior to mass labelling. The tested sample will be mixed with mass conjugate product for final purification.
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Abnova Corporation
Abnova offers Camelid Single Domain Antibody Service for production of target-specific sdAb from naïve camelid VHH library. By using the advanced naïve camelid VHH library screening technology, they screen the library and isolate the sdAb clones for your required antigens. Positive clones are sequenced and validated by ELISA. The selected clones will then be introduced into HEK293 expression vector or E. coli expression vector for transient and scalable sdAb production for many downstream applications.
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Abnova Corporation