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In this study, three antibody clones available from Leinco Technologies (Table 1) were tested for their ability to bind and visualize mpox virus in cell cultures. The work was performed in the lab of Dr. John Connor <http://www.connorlab.com/>, which focuses on understanding how the virus-host interaction works and methods to tip the balance in favor of the host. To do this they aim to determine how viruses hijack infected cells, and how cells defend themselves against viral infection.
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Citations
Leinco Technologies
Leinco Technologies understands the need for reliable, high-performance IVD critical raw materials such as antibodies, proteins, and buffers. Our infectious disease antibodies and proteins catalog includes confirmed matched pairs for ELISA and Lateral Flow applications as well as cutting-edge recombinant antibodies with high specificity and sensitivity. We also offer recombinant antigens and blocking peptides to advance your infectious disease research.
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Immunology
Leinco Technologies
Lot-to-lot reproducible monoclonal antibodies against mouse cell-specific proteins and cytokines are paramount for reproducible results. Depletion can occur naturally or be induced for treatment purposes. Therefore, it is a useful tool in therapeutic, immunotherapy and diagnostic research. It is common practice for researchers to use antibodies to remove a specific cell type to infer its function and mouse cell depletion in vivo experiments are used to establish the role of specific cell types in a variety of immunological processes. Many of these antibodies have been developed by academic and government labs all over the world and have been reported and referenced for use in in vivo studies to deplete a specific cell type.
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Immunology
Leinco Technologies
mAbMods™ recombinant antibodies have been engineered to have identical antigen binding variable domains to those of the traditional clones from which they are derived, but the IgG constant regions have been engineered to be of mouse origin. This reduces immunogenic responses in the mouse which can lead to adverse immunological reactions and gradual loss of activity.
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Antibodies
Leinco Technologies
Consistent and reliable antibodies targeting mouse immune checkpoints and related proteins are essential for advancing cancer research. Achieving lot-to-lot reproducibility is crucial for maintaining the integrity of scientific studies. Leinco Technologies offers a range of functional grade antibodies and is known for our exceptional lot-to-lot reproducibility, minimal endotoxin levels, and absence of detectable impurities. With these high-quality antibodies, researchers can confidently conduct in vivo studies to further our understanding of cancer immunotherapy.
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Cancer
Leinco Technologies
Leinco Technologies offers high-purity research-grade biosimilar antibodies with the same specifications as many therapeutic antibodies. Therapeutic antibodies are widely used for the treatment of diseases, including cancer and autoimmunity.
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Antibodies (Biosimilars)
Leinco Technologies
In vivo grade antibodies have a variety of uses in biological research, from discovery of cell signaling pathways to manipulation of biological systems in animal models for pre-clinical studies. In vivo functional grade antibodies from Leinco Technologies have the highest purity standards in the industry, with low endotoxin levels, and screening to ensure low aggregates. These antibodies are produced in our cGMP and ISO 9001:2015 / ISO 13485:2016 certified facility and are available in custom concentrations and package sizes.
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Antibodies
Leinco Technologies
3Helixs Collagen Hybridising Peptide (CHP) is a synthetic peptide that can specifically bind to denatured collagen by structural recognition of exposed alpha-strands. Their in vivo CHP is conjugated to a near-infrared dye to enable accurate and reliable measurements of collagen turnover in live animal models.
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Peptides
3Helix
CHPs are unique collagen-targeting peptides that only bind to denatured collagen. 3Helixs Collagen Hybridising Peptide is a synthetic peptide that can specifically bind to denatured collagen through hydrogen bonding.
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Peptides
3Helix
Whitepaper by Dr. Lucas Bennink and Dr. Yang Li 3Helix Inc. Salt Lake City, Utah, USA. 84108
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Peptides
3Helix
Whitepaper from Lucas Bennink, Ph.D. and Julian Kessler, Ph.D. 3Helix Inc. Salt Lake City, Utah, USA. 84108
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Peptides
3Helix
Collagen Hybridising Peptides offer a powerful and direct approach to address critical areas of Multiple Myeloma research by specifically visualising and quantifying structural collagen changes.
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Peptides
3Helix
Media with optimised formulation for enhanced differentiation efficiency.
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Cell Culture
Elabscience
ELK Biotechnology, founded in 2013, is a high-tech biological enterprise specialising in life science and immune research, with a portfolio of 8,500+ ELISA kits, 70+ molecular biology products and 10,000+ Antibodies for RUO.
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Supplier Introduction
ELK Biotechnology
ELK provides over 15,000 high-quality antibodies that have been rigorously tested by WB, IHC, IF and other experimental methods.
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Antibodies
ELK Biotechnology
ELK Biotechnology is a high-tech biological company focusing on the development and production of ELISA Kits, antibodies, genome extraction reagents and molecular biology reagents.
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Catalogue
ELK Biotechnology
In Situ Hybridisation (ISH) is a powerful molecular technique used to detect and visualise specific nucleic acid sequences within cells and tissues. Abnova provides a range of ISH probes for research.
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Probes
Abnova Corporation
Abnova provides a nanoCAR-T mRNA service that advances CAR-T cell therapy by integrating its NanoAb™ VHH antibody platform, mRNA IVT technology, and lipid nanoparticle (LNP) delivery. This approach allows precise ex vivo delivery of CAR instructions to T cells via mRNA encapsulated in ionizable lipid nanoparticles.
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Service
Abnova Corporation
Elabscience provides purified antibodies for flow cytometry.
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Flow Cytometry
Elabscience
Elabscience provides over 4,000 flow cytometry antibodies.
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Flow Cytometry
Elabscience
Elabscience offers a comprehensive range of cytokines, including chemokines, interferons, interleukins, tumour necrosis factors, colony-stimulating factors, growth factors and other cytokine-related proteins.
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Cytokines
Elabscience
Elabscience provides a comprehensive selection of over 100 specialised assay kits for multiple cell metabolic research areas including oxidative stress, cell death, energy metabolism, and plant metabolism.
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Metabolism
Elabscience
Elabscience has developed a series of featured products related to key metabolism indicators, following the latest research trends. Their products cover cell death (ferroptosis, cuprotosis, disulfidptosis), mitochondrial function, and energy metabolism.
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Metabolism
Elabscience
Advancing scientific research with high-performance ELISA Kits
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ELISA
Elabscience
Analyse protein expression, functional activity and post-translational modifications.
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Antibody Tools
Elabscience