Learn how MBL International’s Exocap™ Exosome Isolation Kits can help you isolate and enrich exosomes from serum, plasma, and cell culture.
Exosome Research Products
Exosomes are extracellular vesicles secreted from many cells and are found in various body fluids including serum, plasma, saliva and urine. Exosomes consist of lipid bilayer membranes, from 40nm to 100nm in diameter, and contain several proteins and nucleic acid such as microRNA, mRNA and DNA. In recent years, it has been suggested that exosomes may be biomarkers for cancer, diabetes, neurological diseases and various diseases. Exosomes bear specific protein markers of the endosomal pathway, such as tetraspanins (CD63, CD9 and CD81), heat shock proteins (HSP70) and EpCam depending on their cellular origin.
MBLI presents the ExoCap™ kits, which are designed for exosome isolation and enrichment and are optimised for use with serum, plasma and cell culture supernatants. Exosomes are extracellular vesicles secreted by most cell types that contain marker proteins and microRNAs. The kits consist of magnetic particles that are either coupled with antibodies that recognise the exosome surface antigens (CD9, CD63, CD81, or EpCAM) or a new Streptavidin based version enabling the user to conjugate antibodies of their choosing. The kits also contain a treatment buffer, washing/dilution buffer, and exosome elution buffer.
ExoCap™ uses functionalized Magnosphere™ magnetic microparticles for exosome separation. These beads are coated with a proprietary polymer and cofactors which specifically bind to exosomes.
Read More about the ExoCap™ range from MBL International below:
- ExoCap™ Exosome Isolation and Enrichment Kits
- ExoCap™ Streptavidin Kit
- Monoclonal Antibodies for Common Exosomal Markers
MBL International products are exclusively distributed in the UK and Ireland by Caltag Medsystems Ltd.