{"id":10049,"date":"2024-05-03T09:42:23","date_gmt":"2024-05-03T09:42:23","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=10049"},"modified":"2024-06-12T11:49:09","modified_gmt":"2024-06-12T11:49:09","slug":"hepash-standardised-quality-human-hepatocytes","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/hepash-standardised-quality-human-hepatocytes\/","title":{"rendered":"HepaSH\u2122 &#8211; standardised quality Human Hepatocytes!"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Background<\/h2>\n\n\n\n<p>Biopredic International is a well-reputed supplier of human hepatocytes and the exclusive licensee of the renowned HepaRG model.<\/p>\n\n\n\n<p>For over two decades, HepaRG<sup>\u00ae<\/sup> has been instrumental in advancing liver research, earning the admiration and trust of scientists worldwide.<\/p>\n\n\n\n<p>Biopredic were aware of the demand in the scientific community for a HepaRG-similar model from another donor and have worked hard in recent years to develop a hepatic model that can complement HepaRG<sup>\u00ae<\/sup>. Now, Biopredic is delighted to unveil the latest addition to its portfolio: <strong>HepaSH\u2122<\/strong>. As a continuation of the HepaRG<sup>\u00ae<\/sup> model, HepaSH\u2122 sustainable human hepatocytes from multiple donors represents the next evolution in liver research. Biopredic is confident that this model will be just as efficient as HepaRG<sup>\u00ae<\/sup>.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/biopredic\/\" style=\"background-color:#03bf8c\"><strong>Read more about Biopredic<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">About HepaSH\u2122<\/h2>\n\n\n\n<p><strong>HepaSH\u2122<\/strong>, standardised quality Human Hepatocytes, are made sustainable by the technology developed by Biopredic&#8217;s Japanese partner CIEA. This technology allows the obtaining of human hepatocytes \u201cindefinitely\u201d from the same donor by transplanting these human hepatocytes into humanised liver mice. This means once a \u201cdonor\u201d of human hepatocytes was validated by a user, cells from this donor can be supplied as much as needed with a zero stock policy.<\/p>\n\n\n\n<p>HepaSH\u2122 cells have been shown to be a robust and reproducible model of human hepatocytes with long-term viability. Currently, hepatocytes from 3 donors are available and provided as fresh cells ready-to-plate. The HepaSH\u2122 cells have shown functional hepatic performance, i.e. CYP expression and induction.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php?type=Product%20Enquiry&amp;enq=Biopredic%20HepaSH\" style=\"color:#fbc100;background-color:#21318f\"><strong>I&#8217;m interested in HepaSH\u2122!<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p class=\"clear\"><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What sets HepaSH\u2122 apart?<\/h4>\n\n\n\n<ul class=\"wp-block-list\" style=\"font-size:18px\">\n<li>Functional performance<\/li>\n\n\n\n<li>Sustainability over years<\/li>\n\n\n\n<li>Robustness<\/li>\n\n\n\n<li>Consistency across batches<\/li>\n\n\n\n<li>Long-term viability up to 14 days in classical 2D cultures<\/li>\n\n\n\n<li>Multi donor set<\/li>\n\n\n\n<li>Zero stock policy<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Specification<\/h4>\n\n\n\n<figure class=\"wp-block-table alignfull\"><table><tbody><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-230.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">FSH001: 5.106 cell\/vial \u2192 1x 96-multi well plate<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-228.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">Provided as fresh suspended hepatocytes<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-227.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">3 donors are available:<br>Donor 1: Female, Caucasian, 12 years old<br>Donor 2: Male, Caucasian, 3 months<br>Donor 3: Male, African, 31 years old<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-222.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">William E- based cell culture medium<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-223.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">Can be maintained for up to 14 days in 2D culture<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-224.png\" alt=\"\" style=\"width: 100px;\"><\/td><td class=\"has-text-align-left\" data-align=\"left\">2 production sessions\/month<\/td><\/tr><tr><td><img decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-225.png\" alt=\"\" style=\"width: 100px;\"><br><\/td><td class=\"has-text-align-left\" data-align=\"left\">Biopredic&#8217;s commitments: cell viability, number of viable cells, human cell percentage, sterility<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div class=\"wp-block-buttons clear is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php?type=Product%20Enquiry&amp;enq=Biopredic%20HepaSH\" style=\"color:#fbc100;background-color:#21318f\"><strong>Contact us to order H<\/strong><strong>epaSH\u2122<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p class=\"clear\"><\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-alpha-channel-opacity has-background\" style=\"background-color:#21318f;color:#21318f\"\/>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems&nbsp;<\/a>is the distributor of <a href=\"https:\/\/www.caltagmedsystems.co.uk\/biopredic\/\">Biopredic International<\/a> products in the UK and Europe. If you have any questions about these products, please&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biopredic unveils the latest addition to its portfolio: HepaSH\u2122, sustainable human hepatocytes from multiple donors &#8211; next evolution in liver research.<\/p>\n","protected":false},"author":13,"featured_media":10103,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,749],"tags":[883,885,884],"class_list":["post-10049","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-information","category-hepatocytes","tag-biopredic-international","tag-hepash","tag-human-hepatocytes"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=10049"}],"version-history":[{"count":25,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10049\/revisions"}],"predecessor-version":[{"id":10419,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10049\/revisions\/10419"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/10103"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=10049"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=10049"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=10049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}