{"id":10383,"date":"2024-06-07T16:20:09","date_gmt":"2024-06-07T16:20:09","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=10383"},"modified":"2025-07-25T16:14:53","modified_gmt":"2025-07-25T16:14:53","slug":"why-is-the-mhc-monomer-the-ideal-choice-for-your-experimental-design","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/why-is-the-mhc-monomer-the-ideal-choice-for-your-experimental-design\/","title":{"rendered":"Why is the MHC monomer the ideal choice for your experimental design?"},"content":{"rendered":"\n<p>The MHC Monomer is a sub-component of an MHC Tetramer, made up of the MHC complex (\u03b1-chain plus \u03b2-2 microglobulin for class I or \u03b1-chain plus \u03b2-chain for class II) folded together with a specific peptide. Biotinylated Monomers are available for most associated Tetramer products.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-261.png\"><img loading=\"lazy\" decoding=\"async\" width=\"561\" height=\"342\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-261.png\" alt=\"\" class=\"wp-image-10384\" style=\"width:457px;height:auto\" srcset=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-261.png 561w, https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-261-300x183.png 300w\" sizes=\"auto, (max-width: 561px) 100vw, 561px\" \/><\/a><\/figure>\n\n\n\n<p class=\"clear\">Investigators often select MHC monomers to create tetramers in their own labs with alternate labels or to generate smaller tetramer batches. Alternatively, others use monomers for screening or immunisation strategies.<\/p>\n\n\n\n<p>MBLI&#8217;s Biotinylated MHC monomers, Class I or Class II are now available for tetramer construction flexibility and novel applications. For example, the production of metal-labelled tetramers for use with CyTOF instruments using MBLI monomers.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=10&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=Biotinylated%20monomer\" style=\"color:#fbc100;background-color:#21318f\"><strong>Find MHC Monomers<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p class=\"clear\"> <\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-alpha-channel-opacity has-background\" style=\"background-color:#21318f;color:#21318f\"\/>\n\n\n\n<p>Information provided by&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/mbl\/\">MBL<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems&nbsp;<\/a>is the distributor of&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/mbl\/\">MBL&nbsp;<\/a>products in the UK and Ireland. If you have any questions about these products, please&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.<\/p>\n","protected":false},"author":13,"featured_media":12368,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,15],"tags":[67,479,900,224],"class_list":["post-10383","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-information","category-tetramer","tag-mbl-international","tag-mhc","tag-monomer","tag-tetramer"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=10383"}],"version-history":[{"count":4,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10383\/revisions"}],"predecessor-version":[{"id":10388,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10383\/revisions\/10388"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/12368"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=10383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=10383"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=10383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}