{"id":10865,"date":"2024-08-27T12:13:01","date_gmt":"2024-08-27T12:13:01","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=10865"},"modified":"2024-08-27T12:15:46","modified_gmt":"2024-08-27T12:15:46","slug":"what-is-animal-origin-free-medium","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/what-is-animal-origin-free-medium\/","title":{"rendered":"What Is Animal Origin Free Medium?"},"content":{"rendered":"\n<p>To understand what Animal Origin Free Medium means, we first need to understand the different media types available for cell culture.<br><\/p>\n\n\n\n<p>Based on the presence or absence of animal or human-derived components, cell culture media can be classified into:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>serum-contained medium, <\/li>\n\n\n\n<li>serum-free medium,<\/li>\n\n\n\n<li>xeno-free medium, <\/li>\n\n\n\n<li>and chemically defined medium.<\/li>\n<\/ul>\n\n\n\n<p>A chemically defined medium is a cell culture medium where all ingredients are recombinant proteins and chemical compounds.<\/p>\n\n\n\n<p>But Xcell Therapeutics goes one step further and sub-categorises their chemically defined medium into Animal Component Free (ACF) and Animal Origin Free (AOF) medium. <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Animal Component Free (ACF): Animal derivatives may come into contact during the manufacturing process, but are not included in the finished product<\/li>\n\n\n\n<li>Animal Origin Free (AOF): No contact with animal derivatives, from manufacturing to finished product. It represents the highest level of media manufacturing in compliance with regulations.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-277.png\"><img loading=\"lazy\" decoding=\"async\" width=\"748\" height=\"361\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-277.png\" alt=\"\" class=\"wp-image-10869\" srcset=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-277.png 748w, https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-277-300x145.png 300w\" sizes=\"auto, (max-width: 748px) 100vw, 748px\" \/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading clear\">Why Chemically Defined Media?<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Market demand is rapidly increasing due to R&amp;D activities utilising cells across various industries, including cell and gene therapy products (CGT).<\/li>\n\n\n\n<li>The demand for safe products is rising due to concerns over safety issues such as virus contamination and immunogenicity associated with the current use of fetal bovine serum (FBS).<\/li>\n\n\n\n<li>It is recommended to avoid the use of animal-derived reagents worldwide.<\/li>\n\n\n\n<li>Rigorous management and safety assessment data are required to evaluate the potential contamination risks by exogenous agents from biological raw materials.<\/li>\n<\/ul>\n\n\n\n<p class=\"clear\"><\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-alpha-channel-opacity has-background\" style=\"background-color:#21318f;color:#21318f\"\/>\n\n\n\n<p>Information provided by\u00a0Xcell Therapeutics.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems\u00a0<\/a>distributes Xcell Therapeutics\u00a0products in the UK and Ireland. If you have any questions about these products, please\u00a0<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Understand the different types of cell culture media available based on the  presence or absence of animal or human-derived components.<\/p>\n","protected":false},"author":13,"featured_media":10874,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[722,18,926,213],"tags":[],"class_list":["post-10865","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cell-and-gene-therapy","category-cell-culture","category-cell-culture-media","category-exosomes"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10865","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=10865"}],"version-history":[{"count":6,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10865\/revisions"}],"predecessor-version":[{"id":10876,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/10865\/revisions\/10876"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/10874"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=10865"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=10865"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=10865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}