![\"\"](\"https:\/\/kactusbio.com\/cdn\/shop\/files\/CAR-T_Targets_2.png?v=1719435664&width=1000\")
Comprehensive Catalog of CAR-T Target Proteins<\/h2>\n\n\n\n
Leveraging their unique\u00a0SAMS\u2122 protein engineering and expression platform<\/a>, KACTUS has developed a series of high-quality\u00a0CAR-T target protein products, covering a wide range of popular targets such as\u00a0CD19,\u00a0BCMA, and\u00a0MSLN. They also offer various modifications including site-specific labelling, fluorescent labelling, and biotinylation, flexibly meeting diverse research and development needs such as CAR-T affinity assays. If you don’t see what you’re looking for in their catalog, you can always\u00a0request a custom protein.<\/p>\n\n\n\n KACTUS offers a wide range of fluorescent-labelled target proteins that streamline CAR detection by eliminating the need for secondary antibodies, reducing background staining, and increasing efficiency. Their portfolio includes popular target antigens relevant to current CAR-T research, all with high bioactivity, uniformity, and batch-to-batch consistency.<\/p>\n\n\n\n Leveraging their advanced\u00a0protein expression platform, KACTUS also provides a comprehensive solution for\u00a0protein customisation. They offer various modifications such as site-specific labelling, fluorescent labeling (FITC,\u00a0PE, APC, and others), and\u00a0biotinylation, to meet various research requirements such as CAR-T affinity testing.<\/p>\n\n\n\n <\/a>FACS data demonstrating that 100 \u00b5l of\u00a0FITC-Compatible Human CD19 (His Tag)<\/a>\u00a0(10 \u00b5g\/ml) can specifically bind to 1\u00d7106<\/sup>\u00a0Anti-CD19 CAR T cells, resulting in a positive detection rate greater than 96%. FITC-labeled irrelevant protein (100 \u00b5l, 10 \u00b5g\/ml) was used as a negative control.<\/p>\n\n\n\n FACS analysis of Anti-EGFRVIII CAR Expression. 293T cells were transfected with anti-EGFRVIII-scFv and His tag. Cells were incubated with 5 \u00b5g\/ml\u00a0PE-Labeled Human EGFRVIII (His-Avi Tag)<\/a>\u00a0and PE-labelled protein control. Non-transfected 293T cells and PE-labelled protein control were used as negative controls. The PE-labeled Human EGFR VIII specifically binds to Anti-EGFR VIII-CAR T cells, with a positive detection rate of over 99%.<\/p>\n\n\n\n <\/a>FACS analysis of Anti-MSLN-CAR expression. 293T cells were transfected with anti-MSLN-scFv and Fc tag. These cells were stained with 5 \u00b5g\/ml FITC-Labeled Human MSLN (296-580), Fc Tag, and a FITC-labeled protein control. Non-transfected 293T cells and FITC-labeled protein control were used as negative controls. FITC-labeled SA was used to confirm that\u00a0Biotinylated Human MSLN (hFc-Avi Tag)<\/a>\u00a0can specifically bind to Anti-MSLN-CAR 293T cells, resulting in a positive rate greater than 99%.<\/p>\n\n\n\n Caltag Medsystems <\/a>is the distributor of KACTUS products in the UK and Ireland. If you have any questions about these products, please contact us<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":" KACTUS has developed a series of high-quality\u00a0CAR-T target protein products, covering a wide range of popular targets such as\u00a0CD19,\u00a0BCMA, and\u00a0MSLN.<\/p>\n","protected":false},"author":13,"featured_media":11448,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[722,1,641],"tags":[475,976,58],"class_list":["post-11514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cell-and-gene-therapy","category-general-information","category-recombinant-proteins","tag-car-t","tag-kactus","tag-recombinant-proteins"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=11514"}],"version-history":[{"count":14,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11514\/revisions"}],"predecessor-version":[{"id":11689,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11514\/revisions\/11689"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/11448"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=11514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=11514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=11514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Product Features<\/h3>\n\n\n\n
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Product Applications<\/h3>\n\n\n\n
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Product Validation Data<\/h2>\n\n\n\n
FITC-Compatible Human CD19<\/h3>\n\n\n\n
![\"\"](\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-332-1024x330.png\")
<\/figure>\n\n\n\nPE-Labeled Human EGFRVIII<\/a><\/h3>\n\n\n\n
![\"\"](\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-333-1024x331.png\")
<\/figure>\n\n\n\nBiotinylated Human MSLN\/Mesothelin<\/h3>\n\n\n\n
![\"\"](\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-334-1024x341.png\")
<\/a><\/figure>\n\n\n\n
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