{"id":11816,"date":"2025-03-26T16:42:00","date_gmt":"2025-03-26T16:42:00","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=11816"},"modified":"2025-03-26T16:42:00","modified_gmt":"2025-03-26T16:42:00","slug":"cas9-expressing-primary-cells-gpcr-expressing-cell-lines","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/cas9-expressing-primary-cells-gpcr-expressing-cell-lines\/","title":{"rendered":"Cas9 Expressing Primary Cells &amp; GPCR Expressing Cell Lines"},"content":{"rendered":"\n<figure class=\"wp-block-image is-resized\"><img decoding=\"async\" src=\"https:\/\/www.neuromics.com\/site\/images\/A8x12dabx71x1.jpg\" alt=\"\" style=\"width:419px;height:auto\"\/><figcaption class=\"wp-element-caption\"><em>Human retinal microvascular endothelial cells (HRMECs) in culture.<\/em><\/figcaption><\/figure>\n\n\n\n<p>Neuromics is proud to introduce their newest pioneering research tools &#8211;\u00a0human Cas9 expressing primary cells and GPCR expressing cell lines. With these modifications, the cells are valuable and versatile options for drug discovery, studying disease mechanisms, and countless other applications.<\/p>\n\n\n\n<p>Their Cas9 expressing human primary cells\u00a0have been genetically modified to express the Cas9 protein in a stable manner. Engineered to continuously produce and maintain the expression of the Cas9 protein, they can be used for precise and consistent CRISPR-based genome editing.<\/p>\n\n\n\n<p class=\"clear\">Neuromics are starting by offering six types of Cas9 expressing primary cells, including\u00a0endothelial cells\u00a0and\u00a0fibroblasts. However, they will add dozens more in the future. Please\u00a0<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>\u00a0if there are any other types you need.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/?group_1=All&amp;group_2=83&amp;supplier=113&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=cas9\" style=\"color:#fbc100;background-color:#21318f\"><strong>Explore the Cas9 Primary Cells<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p>G-Protein Coupled Receptors (GPCRs) are at the forefront of modern drug discovery research, playing a vital role in various signal transduction pathways. Neuromics are starting by offering two of the most studied and used cell lines, GPCR expressing\u00a0HEK293\u00a0and\u00a0CHO-K1\u00a0cells.<\/p>\n\n\n\n<p>These cells are prepared to express G protein-coupled receptors (GPCRs) of interest, enabling them to serve as critical platforms for the production, study, and characterisation of proteins. The exact expression parameters are set by the customer, with over 450 options available. To get the cells you need, you will need to provide us with the protein accession number you are looking for.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/?group_1=All&amp;group_2=26&amp;supplier=113&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=GPCR\" style=\"color:#21318f;background-color:#fbc100\"><strong>View the GPCRs Cell Lines<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p>Along with the new cells, they also have introduced new media products to keep the cells healthy and expressing the right things. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/?group_1=All&amp;group_2=19&amp;supplier=113&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=cas9\" style=\"color:#fbc100;background-color:#21318f\"><strong>Browse the Cas9 Media<\/strong><\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/?group_1=All&amp;group_2=19&amp;supplier=113&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=GPCR\" style=\"color:#21318f;background-color:#fbc100\"><strong>Browse the GPCRs Media<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\" style=\"margin-top:var(--wp--preset--spacing--50);margin-bottom:var(--wp--preset--spacing--50)\"\/>\n\n\n\n<p>Information originally posted by Neuromics at: <a href=\"https:\/\/www.neuromics.com\/introducing-cas9-expressing-primary-cells-gpcr-expressing-cell-lines\">https:\/\/www.neuromics.com\/introducing-cas9-expressing-primary-cells-gpcr-expressing-cell-lines<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems\u00a0<\/a>is the distributor of\u00a0<a href=\"https:\/\/www.caltagmedsystems.co.uk\/neuromics\/\">Neuromics <\/a>products in the UK and Ireland. If you have any questions about these products, please\u00a0<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neuromics is proud to introduce their newest pioneering research tools &#8211;\u00a0human Cas9 expressing primary cells and GPCR expressing cell lines.<\/p>\n","protected":false},"author":13,"featured_media":11820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[722,18,926,906,990,1,904],"tags":[991,1006,1005,568,856,946],"class_list":["post-11816","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cell-and-gene-therapy","category-cell-culture","category-cell-culture-media","category-cell-lines","category-crispr","category-general-information","category-primary-cells","tag-cas9","tag-cell-lines","tag-gpcrs","tag-media","tag-neuromics","tag-primary-cells"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=11816"}],"version-history":[{"count":4,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11816\/revisions"}],"predecessor-version":[{"id":11821,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/11816\/revisions\/11821"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/11820"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=11816"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=11816"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=11816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}