{"id":12030,"date":"2025-04-07T21:04:25","date_gmt":"2025-04-07T21:04:25","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=12030"},"modified":"2025-04-07T21:04:32","modified_gmt":"2025-04-07T21:04:32","slug":"rna-mango-rna-tracking-visualisation","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/rna-mango-rna-tracking-visualisation\/","title":{"rendered":"RNA Mango – RNA Tracking & Visualisation"},"content":{"rendered":"\n

Overview<\/h2>\n\n\n\n
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The most advanced RNA tracking, visualisation and pull down technology.<\/strong> Technology for studying the diverse cellular roles of RNA has lagged behind the tools for studying DNA and proteins, but innovative researchers are working to change that! One such researcher is Dr. Peter Unrau of Simon Fraser University<\/a>. He and his team have created RNA Mango, a novel technology with a number of useful applications.<\/p>\n\n\n\n

Products Available:<\/h3>\n\n\n\n
Product Name<\/th>Cat. No.<\/th>Size<\/th><\/tr><\/thead>
TO1-3PEG-Biotin Fluorophore<\/td>ABM-G7955<\/a><\/td>250 \u00b5M (100 \u00b5l)<\/td><\/tr>
TO1-3PEG-Desthiobiotin Fluorophore<\/td>ABM-G7956<\/a><\/td>250 \u00b5M (100 \u00b5l)<\/td><\/tr>
TO3-3PEG-Biotin Fluorophore<\/td>ABM-G7959<\/a><\/td>250 \u00b5M (100 \u00b5l)<\/td><\/tr>
YO3-3PEG-Biotin Fluorophore<\/td>ABM-G7957<\/a><\/td>250 \u00b5M (100 \u00b5l)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

* Click here for data on binding affinity to Mango and Peach aptamers<\/a><\/strong><\/p>\n\n\n\n

Key Features<\/h2>\n\n\n\n

RNA Mango technology is based on the specific binding of the RNA Mango Aptamer and a Thizole Orange (TO) bi-functional dye. The main features of this technology is the tight binding between the dye and aptamer (KD \u2248 3nM) , and the strong ~1000X enhancement of the dye\u2019s fluorescence when bound to the Mango aptamer (Fluorescent enhancement FE=1,100).

The Thizole Orange (TO) dye has a number of other desirable properties including:<\/p>\n\n\n\n