{"id":2443,"date":"2017-04-24T13:09:00","date_gmt":"2017-04-24T13:09:00","guid":{"rendered":"http:\/\/www.caltagmedsystems.co.uk\/information\/?p=2443"},"modified":"2022-06-21T15:25:31","modified_gmt":"2022-06-21T15:25:31","slug":"october-2016-the-antibody-update","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/october-2016-the-antibody-update\/","title":{"rendered":"October 2016: The Antibody Update"},"content":{"rendered":"

The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy<\/strong><\/p>\n

Autophagy<\/a> is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi\u2019s work in autophagy has proven to be fundamental to cell biologists and eventually led to a great impact in medicine. Ohsumi\u2019s work showed that autophagy exists in yeast cells through his work, and eventually applied the same methods to show autophagy\u2019s importance in human cells. Malfunctions in autophagy have been linked to Parkinson\u2019s disease, type-2 diabetes, and other disorders associated with aging. Check out more about Yoshinori Ohsumi\u2019s Nobel Prize work here<\/a>.<\/p>\n

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Combination Immunotherapy Is on the Rise
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A new combination immunotherapy<\/a> has been shown to eradicate large tumors in mice. Scientists at MIT combined 4 components in the antitumor cocktail; a tumor antigen targeting antibody, a modified recombinant interleukin-2 signaling molecule with an extended half-life, anti-PD-1 antibodies<\/a>, and a vaccine that designed to increase traffic to lymph nodes and boost T-cell response. This immunotherapy was able to boost the immune system\u2019s tumor antigen uptake and thus its ability to target other cancerous cells. The treatment effectively reduced large tumors and transplanted tumors in the mouse models used.<\/p>\n

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Brazilian Scientists Make the Decision to Release Bacteria-Infected Mosquitoes to Combat Zika<\/strong><\/p>\n

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in Brazil plan to use Wolbachia pipientis <\/em>to combat the population of mosquitoes that are helping to propagate Zika throughout the country. These bacteria have negative effects on insects\u2019 ability to reproduce, and also to harbor viral infection. By developing a modified strain that is able to infectAedes aegypti <\/em>(the mosquitoes that commonly carry Zika and Dengue viruses), it may be possible to sap the mosquito population to help prevent further spread of infection.Wolbachia <\/em>cannot infect humans, which makes this approach seem less dangerous, but we can only hope that there will be few
\nunforeseen consequences. Check out the full article here<\/a>.<\/p>\n

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Find out how ProSci can help your Antibody needs today!<\/a><\/p>\n

 From ProSci<\/code><\/p>\n","protected":false},"excerpt":{"rendered":"

The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi\u2019s work in autophagy has proven to<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[132],"tags":[161,69,7,158,186,171,77,190,139,163,162],"class_list":["post-2443","post","type-post","status-publish","format-standard","hentry","category-antibodies","tag-antbody-update","tag-autophagy","tag-cancer","tag-immunotherapy","tag-neuroscience","tag-nobel-prize","tag-prosci","tag-sfn","tag-therapeutics","tag-virus","tag-zika"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/2443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=2443"}],"version-history":[{"count":7,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/2443\/revisions"}],"predecessor-version":[{"id":6746,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/2443\/revisions\/6746"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=2443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=2443"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=2443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}