{"id":4539,"date":"2019-04-01T06:54:30","date_gmt":"2019-04-01T06:54:30","guid":{"rendered":"http:\/\/www.caltagmedsystems.co.uk\/information\/?p=4539"},"modified":"2024-04-17T12:01:05","modified_gmt":"2024-04-17T12:01:05","slug":"clinically-relevant-mesenchymal-stem-cell-populations-for-research-2","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/clinically-relevant-mesenchymal-stem-cell-populations-for-research-2\/","title":{"rendered":"Clinically Relevant Mesenchymal Stem Cell Populations For Research"},"content":{"rendered":"<p>Renovos offer unique Bone Marrow Mesenchymal Stem Cells, which have been isolated from patients with Osteoarthritis, for research purposes.<\/p>\n<p>Mesenchymal stem cells (MSCs) or skeletal stem cells, of bone marrow origin, have been used as research tools for decades and within the past 10 years progressed to hundreds of clinical trials for various regenerative and immunomodulatory approaches.<\/p>\n<p>The MSC research field is expanding rapidly, however the outcomes of various in vitro and in vivo studies are not directly comparable due to variability in the stem cell source used, purity, or even irrelevant donor selection.<\/p>\n<p>By applying clonal culture techniques, Renovos MSCs are supplied at the highest purity and at an early passage, allowing for cell expansion.<\/p>\n<p>Renovos stem cells offer the following key advantages:<\/p>\n<p>\u2022 Clinically relevant age range for testing therapeutics\/biomaterials designed for the elderly,\u00a0 adults or adolescents<\/p>\n<p>\u2022 Donors with clinical presentations -osteoarthritis; as a suitable model for relevant\u00a0 drug\/biomaterial testing<\/p>\n<p>\u2022 Early passages and guaranteed cell expansion &#8211; P2 stocks, &gt;10 population doublings under\u00a0 optimal conditions<\/p>\n<p>\u2022 Detailed flow cytometric analysis &#8211; for expression of common mesenchymal stem\/progenitor\u00a0 cell markers, including for STRO-1, CD73,\u00a0 \u00a0 \u00a0CD90, CD105<\/p>\n<p>\u2022 Multipotency &#8211; tested for osteo-, chondro- and adipogenic differentiation in vitro<\/p>\n<p>\u2022 Pathogen free &#8211; HBV\/HCV\/HIV, bacteria, mycoplasma and fungi free<\/p>\n<p>\u2022 Various levels of purity of the stem cell populations available upon request: unselected mesenchymal, STRO-1 cell-enriched, Clonal<\/p>\n<p>\u2022 Inventory available upon request, detailing lot availability, donor age and sex. Lot specific Certificate of Analysis are also available to view.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/Renovos.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-4540 aligncenter\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/Renovos.jpg\" alt=\"\" width=\"418\" height=\"321\" srcset=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/Renovos.jpg 418w, https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/Renovos-300x230.jpg 300w\" sizes=\"auto, (max-width: 418px) 100vw, 418px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>Currently, the following products are available:<\/p>\n<p>\u2022 Bone Marrow Mesenchymal Stem Cells &#8211; Osteoarthritic, 500,000 Cells<br \/>\nProduct Code: REN-OA-500<br \/>\nDisease State: Osteoarthritic<\/p>\n<p>\u2022 Bone Marrow Mesenchymal Stem Cells &#8211; Osteoarthritic, 1 million Cells<br \/>\nProduct Code: REN-OA-1M<br \/>\nDisease State: Osteoarthritic<\/p>\n<p>Please do contact us if you require MSCs from an alternate disease state, as we may be able to provide a custom product.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Renovos offer unique Bone Marrow Mesenchymal Stem Cells, which have been isolated from patients with Osteoarthritis, for research purposes. Mesenchymal stem cells (MSCs) or skeletal stem cells, of bone marrow origin, have been used as research tools for decades and<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[854],"class_list":["post-4539","post","type-post","status-publish","format-standard","hentry","category-general-information","tag-renovos"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/4539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=4539"}],"version-history":[{"count":3,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/4539\/revisions"}],"predecessor-version":[{"id":4543,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/4539\/revisions\/4543"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=4539"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=4539"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=4539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}