{"id":5203,"date":"2019-08-29T12:07:02","date_gmt":"2019-08-29T12:07:02","guid":{"rendered":"http:\/\/www.caltagmedsystems.co.uk\/information\/?p=5203"},"modified":"2020-03-16T13:25:28","modified_gmt":"2020-03-16T13:25:28","slug":"mhc-class-i-ii-tetramers-mhc-monomers-and-cd1d-tetramers","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/mhc-class-i-ii-tetramers-mhc-monomers-and-cd1d-tetramers\/","title":{"rendered":"MHC Class I &#038; II Tetramers, MHC Monomers and CD1d Tetramers"},"content":{"rendered":"<p><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.mblintl.com\/products\/media\/wysiwyg\/New_folder_2017\/TetramerFlyer10_1.PNG\" alt=\"tetramer\" \/><\/p>\n<p>TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC\/peptide tetramers to be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet&#x2122; 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy using our MHC Multimers.<\/p>\n<ul class=\"unstyled\">\n<li>MBL tetramers\u00a0offer Superior Specificity with\u00a0\u03b13 Mutation<\/li>\n<li>Class I\u00a0and\u00a0Class II\u00a0Available<\/li>\n<li>PE,\u00a0APC\u00a0and\u00a0BV421\u00a0Conjugates Available<\/li>\n<li>Available MHC Alleles<\/li>\n<li>Custom Services Available<\/li>\n<\/ul>\n<h3>Learn about the types of MHC Molecules<\/h3>\n<ul>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/tetramers\/\">Tetramers<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/monomers\/\">Monomers<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/new-alleles-added-to-the-mhc-class-i-tetramer-range\/\">Class I<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/class-ii-mhc-tetramers-available-from-mbl-international\/\">Class II<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/cd1d\/\">CD1d<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/non-classical-mhc\/\">Non-Classical<\/a><\/li>\n<li><a href=\"https:\/\/www.caltagmedsystems.co.uk\/downloads\/Tetramer_References.xlsx\">Tetramer Citations<\/a><\/li>\n<\/ul>\n<h3>Superior Specificity with Patented \u03b13 Mutation<\/h3>\n<p><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.mblintl.com\/products\/media\/wysiwyg\/HLA-A0201-CMV-pp65-Tetramer_2.png\" alt=\"Impact of \u00ce\u00b13 Mutation\" \/><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchwords=tetramer&amp;PG_ID=0&amp;CO_ID=0&amp;HT_ID=0&amp;AT_ID=0&amp;ST_ID=0&amp;MF_ID=10\"><strong>See All Tetramer and Monomer Products<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC\/peptide tetramers to be used<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,15],"tags":[46,67,224],"class_list":["post-5203","post","type-post","status-publish","format-standard","hentry","category-general-information","category-tetramer","tag-flow-cytometry","tag-mbl-international","tag-tetramer"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5203","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=5203"}],"version-history":[{"count":8,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5203\/revisions"}],"predecessor-version":[{"id":5685,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5203\/revisions\/5685"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=5203"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=5203"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=5203"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}