{"id":528,"date":"2015-11-17T14:09:50","date_gmt":"2015-11-17T14:09:50","guid":{"rendered":"http:\/\/caltagmedsystems.co.uk\/information\/?p=528"},"modified":"2023-07-04T15:03:08","modified_gmt":"2023-07-04T15:03:08","slug":"human-hepatic-stellate-cells","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/human-hepatic-stellate-cells\/","title":{"rendered":"Human Hepatic Stellate Cells"},"content":{"rendered":"<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/sciencell\/\">ScienCell\u2019s<\/a> Human Hepatic Stellate Cells (Product Code: <a href=\"http:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=613790\">SC-5300<\/a>) cultured in Stellate Cell Medium (Product Code: <a href=\"http:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=612349\">SC-5301<\/a>) is an optimal model for many research areas including liver injury, hepatic development, regeneration, xenobiotic responses, intermediary metabolism, and immunoregulation.<\/p>\n<p>Studying HHSteC will lead to therapies for hepatic fibrosis and may help to reduce morbidity and mortality in patients with chronic liver injury.<\/p>\n<ul>\n<li>Isolated from human liver<\/li>\n<li>Each vial contains &gt;5 x 105 cells in 1 ml volume<\/li>\n<li>Guaranteed to further expand for 15 population doublings<\/li>\n<li>Recommended medium: Stellate Cell Medium (Product Code: <a href=\"http:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=612349\">SC-5301<\/a>)<\/li>\n<\/ul>\n<p><a href=\"http:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchwords=hepat&amp;MF_ID=53&amp;PG_ID=12&amp;CO_ID=0&amp;AT_ID=0&amp;ST_ID=0&amp;HT_ID=9\">View Hepatic Cell System &gt;&gt;<\/a><\/p>\n<p><a href=\"http:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchwords=stellate&amp;MF_ID=0&amp;PG_ID=12&amp;CO_ID=0&amp;AT_ID=0&amp;ST_ID=0&amp;HT_ID=9\">View Stellate Cells &gt;&gt;<\/a><\/p>\n<p><a class=\"notion-link-token notion-focusable-token notion-enable-hover\" tabindex=\"0\" href=\"https:\/\/www.caltagmedsystems.co.uk\/\" rel=\"noopener noreferrer\" data-token-index=\"0\"><span class=\"link-annotation-unknown-block-id--1999865189\">Caltag Medsystems <\/span><\/a>is the distributor of <a href=\"https:\/\/www.caltagmedsystems.co.uk\/sciencell\/\">ScienCell<\/a> products in the UK and Ireland. If you have any questions about these products, please <a class=\"notion-link-token notion-focusable-token notion-enable-hover\" tabindex=\"0\" href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\" rel=\"noopener noreferrer\" data-token-index=\"5\"><span class=\"link-annotation-unknown-block-id--1821305553\">contact<\/span><\/a> <a class=\"notion-link-token notion-focusable-token notion-enable-hover\" tabindex=\"0\" href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\" rel=\"noopener noreferrer\" data-token-index=\"7\"><span class=\"link-annotation-unknown-block-id--1821305553\">us<\/span><\/a>.<\/p>\n<p><strong>Featured Publications:<\/strong><\/p>\n<p>Che J, Chan ES, Cronstein BN. (2007) &#8220;Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1\/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway.&#8221; Mol Pharmacol. 72: 1626-36.<\/p>\n<p>Mart\u00edn-V\u00edlchez S, Sanz-Cameno P, Rodr\u00edguez-Mu\u00f1oz Y, Majano PL, Molina-Jim\u00e9nez F, L\u00f3pez-Cabrera M, Moreno-Otero R, Lara-Pezzi E. (2008) &#8220;The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells.&#8221; Hepatology. 47: 1872-83.<\/p>\n<p>Semela D, Das A, Langer D, Kang N, Leof E, Shah V. (2008) &#8220;Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function.&#8221; Gastroenterology. 135: 671-9.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ScienCell\u2019s Human Hepatic Stellate Cells (Product Code: SC-5300) cultured in Stellate Cell Medium (Product Code: SC-5301) is an optimal model for many research areas including liver injury, hepatic development, regeneration, xenobiotic responses, intermediary metabolism, and immunoregulation. Studying HHSteC will lead<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[],"class_list":["post-528","post","type-post","status-publish","format-standard","hentry","category-cell-culture"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/528","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=528"}],"version-history":[{"count":6,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/528\/revisions"}],"predecessor-version":[{"id":7552,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/528\/revisions\/7552"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=528"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=528"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}