{"id":5374,"date":"2019-10-22T09:13:40","date_gmt":"2019-10-22T09:13:40","guid":{"rendered":"http:\/\/www.caltagmedsystems.co.uk\/information\/?p=5374"},"modified":"2022-03-10T13:40:26","modified_gmt":"2022-03-10T13:40:26","slug":"olfr734-mediates-glucose-metabolism-as-a-receptor-of-asprosin","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/olfr734-mediates-glucose-metabolism-as-a-receptor-of-asprosin\/","title":{"rendered":"OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin"},"content":{"rendered":"<p>Asprosin is a fasting-induced hormone that increases plasma glucose levels in the liver. It also stimulates appetite in the hypothalamus by activating the cAMP signaling pathway via an unknown G protein-coupled receptor (GPCR). In a recent study, the lab of Yiguo Wang (Tsinghua University, 100084 Beijing, China) identifies the multipass G protein-coupled receptor olfactory receptor OLFR734, as the Asprosin receptor in liver. The Asprosin-OLFR734 axis plays a key role in hepatic glucose homeostasis during fasting and in obesity.<\/p>\n<p>AdipoGen Life Sciences provides a recombinant protein, monoclonal antibodies and a detection set to study Asprosin.<\/p>\n<p>&#8211; Asprosin (human) (rec.) (His) (Prod. No. <a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchtype=all&amp;searchwords=AG-40B-0174T\">AG-40B-0174T<\/a>)<\/p>\n<p>&#8211; anti-Asprosin, mAb (Birdy-1) (Prod. No. <a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchtype=all&amp;searchwords=AG-20B-0073\">AG-20B-0073<\/a>)<\/p>\n<p>&#8211; anti-Asprosin (human), mAb (Birdy-2) (Prod. No. <a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchtype=all&amp;searchwords=AG-20B-0074\">AG-20B-0074<\/a>)<\/p>\n<p>&#8211; Asprosin (human) Matched Pair Detection Set (Prod. No. <a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/search_results.php?searchtype=all&amp;searchwords=AG-46B-0011\">AG-46B-0011<\/a>)<\/p>\n<p>LIT: OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1550413119302621?via%3Dihub\">E. Li, et al.; Cell Metabolism 30, 1 (2019)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Asprosin is a fasting-induced hormone that increases plasma glucose levels in the liver. It also stimulates appetite in the hypothalamus by activating the cAMP signaling pathway via an unknown G protein-coupled receptor (GPCR). In a recent study, the lab of<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[279],"class_list":["post-5374","post","type-post","status-publish","format-standard","hentry","category-general-information","tag-adipogen"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=5374"}],"version-history":[{"count":1,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5374\/revisions"}],"predecessor-version":[{"id":5375,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5374\/revisions\/5375"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=5374"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=5374"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=5374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}