{"id":5921,"date":"2020-04-21T11:49:18","date_gmt":"2020-04-21T11:49:18","guid":{"rendered":"http:\/\/www.caltagmedsystems.co.uk\/information\/?p=5921"},"modified":"2023-08-03T11:09:04","modified_gmt":"2023-08-03T11:09:04","slug":"unique-human-ace2-monoclonal-blocking-antibody","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/unique-human-ace2-monoclonal-blocking-antibody\/","title":{"rendered":"UNIQUE  Human ACE2 Monoclonal Blocking Antibody"},"content":{"rendered":"\n<p><strong>AdipoGen Life Sciences&#8217;<\/strong>\u00a0anti-ACE2 (human), mAb (blocking) (AC384) (preservative free) (Prod. No. <a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=1186481&amp;group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=AG-20A-0037PF\">AG-20A-0037PF<\/a>)\u00a0is a monoclonal antibody that recognises human ACE2 and works specifically in ELISA, Western Blot and Functional Application. The antibody blocks\u00a0the binding of human ACE2 to the Spike protein of SARS-Cov-2.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/adipogen.com\/pub\/media\/wysiwyg\/Landing-Pages\/COVID-19\/ag-20a-0037pf-blocking_assays-400px.png\" alt=\"anti-ACE2 Blocking\"\/><figcaption class=\"wp-element-caption\"><strong>Figure:\u00a0<\/strong>Binding of ACE2 (human) to the Spike protein of SARS-CoV-2 is inhibited by the antibody anti-ACE2 (human), mAb (blocking) (AC384) (AG-20A-0037PF).<\/figcaption><\/figure>\n\n\n\n<p><b>Method:\u00a0<\/b>SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.) (<a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=1186493&amp;group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=AG-40B-0194\">AG-40B-0194<\/a>) is coated on an ELISA plate at 1\u00b5g\/ml. ACE2 (human), mAb (blocking) (AC384) (<a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/product_detail.php?CI_ID=1186481&amp;group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=AG-20A-0037PF\">AG-20A-0037PF<\/a>) or an unrelated mAb Control are added (starting at 40\u00b5g\/ml with a two-fold serial dilution) together with 500ng\/\u00b5l of ACE2 (human) (<a href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=AG-40B-0192\">AG-40B-0192<\/a>). After incubation for 1h at RT, the binding was detected using an anti-FLAG antibody (HRP).<\/p>\n\n\n\n<p>Originally posted on&nbsp;<a href=\"https:\/\/adipogen.com\/covid-19\">adipogen.com\/covid-19<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems&nbsp;<\/a>is the distributor of&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/adipogen\/\">Adipogen<\/a>&nbsp;products in the UK and Ireland. If you have any questions about these products, please&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact<\/a>&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">us<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anti-ACE2 (human), mAb (blocking) (AC384) (preservative free) is a monoclonal antibody that recognises human ACE2 and blocks its binding to SARS-Cov-2.<\/p>\n","protected":false},"author":13,"featured_media":7867,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[517],"tags":[279,515],"class_list":["post-5921","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","tag-adipogen","tag-covid-19"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5921","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=5921"}],"version-history":[{"count":2,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5921\/revisions"}],"predecessor-version":[{"id":7866,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/5921\/revisions\/7866"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/7867"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=5921"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=5921"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=5921"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}