{"id":8881,"date":"2023-10-17T15:50:27","date_gmt":"2023-10-17T15:50:27","guid":{"rendered":"https:\/\/www.caltagmedsystems.co.uk\/information\/?p=8881"},"modified":"2023-10-17T15:50:28","modified_gmt":"2023-10-17T15:50:28","slug":"in-vivo-transfection-experiment-reagents","status":"publish","type":"post","link":"https:\/\/www.caltagmedsystems.co.uk\/information\/in-vivo-transfection-experiment-reagents\/","title":{"rendered":"In Vivo Transfection Experiment Reagents"},"content":{"rendered":"\n<p><a rel=\"noreferrer noopener\" href=\"http:\/\/hoxh.mjt.lu\/lnk\/AV0AACbuMggAAcuEatgAALYTG7YAASJ_BiUAJSy6AAf6xQBlJlYDL3HIDKbATuib3bpA6ks8qgAHl8k\/3\/sqlvRmNrJ6FEzvAGvwsmAw\/aHR0cHM6Ly9vemJpb3NjaWVuY2VzLmNvbS8\" target=\"_blank\">OZ Biosciences<\/a> offers solutions to improve your <em>In Vivo<\/em> Transfections or Infections.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/oz-biosciences-and-magnofection\/\">What is <em>In Vivo<\/em> Magnetofection?\u00a0<\/a><\/strong><\/h3>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile\" style=\"grid-template-columns:auto 18%\"><div class=\"wp-block-media-text__content\">\n<p><strong><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/oz-biosciences-and-magnofection\/\"><em>In vivo<\/em> Magnetofection&#x2122;<\/a><\/strong> has been designed for<em> in vivo<\/em> targeted transfection and infection. This original system combines<strong> magnetic nanoparticles<\/strong> and nucleic acid vectors or viruses that will be retained after injection at the magnetically targeted site. The <strong>magnetic force <\/strong>will enhance the uptake of the magnetic particles by the target tissue and thus <strong>improve the efficiency of transfection<\/strong>. The nanoparticles are fully biodegradable, making this process <strong>non-toxic. \u00a0<\/strong><\/p>\n<\/div><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"131\" height=\"112\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-86.png\" alt=\"\" class=\"wp-image-8882 size-full\"\/><\/figure><\/div>\n\n\n\n<h4 class=\"wp-block-heading clear\"><strong>Problems you may encounter with systemic gene vector administration<\/strong>:<\/h4>\n\n\n\n<ul class=\"wp-block-list\" style=\"font-size:16px\">\n<li style=\"font-size:16px\"><strong>Lack of specificity<\/strong> toward the pathological site<\/li>\n\n\n\n<li><strong>The necessity of a large dose of vector<\/strong> to achieve high local concentration<\/li>\n\n\n\n<li style=\"font-size:16px\">Non-specific <strong>toxicity<\/strong><\/li>\n\n\n\n<li><strong>Inactivation<\/strong> of vectors due to undesired interactions with the environment<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How <em>In Vivo<\/em> Magnetofection can solve it<\/strong>:<\/h4>\n\n\n\n<ul class=\"wp-block-list\" style=\"font-size:16px\">\n<li>The gene vector and nanobead complex will be retained at the target site thanks to a magnetic force allowing a <strong>specific transfection\/infection<\/strong><\/li>\n\n\n\n<li>Nucleic acid or virus <strong>doses needed are reduced<\/strong>, making it a <strong>non-toxic <\/strong>process<\/li>\n\n\n\n<li>The magnetic force will enhance the uptake of the magnetic particle complex by the target tissue, which <strong>reduces the process time of delivery<\/strong> and thus the inactivation of vectors by the environment<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Discover OZ Biosciences&#8217; In Vivo Magnetofection Products<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>For In Vivo targeted Transfection of nucleic acids (DNA, RNA and oligonucleotides)<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-87.png\"><img loading=\"lazy\" decoding=\"async\" width=\"152\" height=\"82\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-87.png\" alt=\"\" class=\"wp-image-8883\" srcset=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-87.png 152w, https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-87-150x82.png 150w\" sizes=\"auto, (max-width: 152px) 100vw, 152px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Rat intestine transfection with in vivo PoyMag<\/em><\/figcaption><\/figure>\n\n\n\n<div class=\"wp-block-buttons clear is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=polymag\" style=\"color:#fbc100;background-color:#21318f\">In Vivo PolyMag<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=dogtormag\" style=\"color:#fbc100;background-color:#21318f\">In Vivo DogtorMag<\/a><\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading clear\"><strong>For In Vivo targeted Infection (LentiVirus\/Retroviral, Adenoviral and Adeno Associated Viral (AAV) Vectors)<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-88.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-88.png\" alt=\"\" class=\"wp-image-8884\" style=\"width:219px;height:90px\" width=\"219\" height=\"90\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Infection of rat embryo with GFP-lentivirus coupled with in vivo ViroMag<\/em><\/figcaption><\/figure>\n\n\n\n<div class=\"wp-block-buttons clear is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button clear\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=viromag\" style=\"color:#fbc100;background-color:#21318f\">In Vivo ViroMag<\/a><\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading clear\"><strong>For In Vivo targeted Gene Silencing (transfection of siRNA, miRNA)<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-89.png\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-content\/uploads\/image-89.png\" alt=\"\" class=\"wp-image-8885\"\/><\/a><\/figure>\n\n\n\n<div class=\"wp-block-buttons clear is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button clear\"><a class=\"wp-block-button__link has-text-color has-background wp-element-button\" href=\"https:\/\/www.caltagmedsystems.co.uk\/pricing_ordering\/index.php?group_1=All&amp;group_2=All&amp;supplier=All&amp;clonality=All&amp;host=All&amp;species=All&amp;applications=All&amp;regulatory_status=All&amp;searchwords=silencemag\" style=\"color:#fbc100;background-color:#21318f\">In Vivo SilenceMag<\/a><\/div>\n<\/div>\n\n\n\n<p class=\"clear\"> <\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-alpha-channel-opacity has-background\" style=\"background-color:#21318f;color:#21318f\"\/>\n\n\n\n<p>Information provided by&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/ozbiosciences\/\">OZ Biosciences<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.caltagmedsystems.co.uk\/\">Caltag Medsystems&nbsp;<\/a>is the distributor of&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/ozbiosciences\/\">OZ Biosciences<\/a>&nbsp;products in the UK and Ireland. If you have any questions about these products, please&nbsp;<a href=\"https:\/\/www.caltagmedsystems.co.uk\/contact.php\">contact us<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OZ Biosciences offers solutions to improve your In Vivo Transfections or Infections.<\/p>\n","protected":false},"author":13,"featured_media":8906,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,438],"tags":[566,545,542,440],"class_list":["post-8881","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-information","category-transfection","tag-in-vivo","tag-magnetofection","tag-oz-biosciences","tag-transfection"],"_links":{"self":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/8881","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/comments?post=8881"}],"version-history":[{"count":21,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/8881\/revisions"}],"predecessor-version":[{"id":8907,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/posts\/8881\/revisions\/8907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media\/8906"}],"wp:attachment":[{"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/media?parent=8881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/categories?post=8881"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.caltagmedsystems.co.uk\/information\/wp-json\/wp\/v2\/tags?post=8881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}