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IQ Products

UK and Ireland Distributor of IQ Products - diagnostic flow cytometry manufacturer specialising in Women's Health and pregnancy related disorders

IQ Products, a developer and manufacturer of a range of antibody based diagnostic products located in The Netherlands, is committed to bringing innovative products to the market for research & diagnostics in human healthcare. Their products are manufactured to meet the highest quality standards of CE, ISO 13485 and FDA requirements. IQ Products provide smart, innovative, and reliable diagnostic solutions in the fields of sepsis, inflammation, transplantation, perinatal diagnostics, oncology and routine flow cytometry.

Antibodies

IQ Products supply a wide range of conjugated antibodies and reagents for immunophenotyping and immune monitoring. This includes single, dual and triple colour antibodies for immunophenotyping as well as lysing, fixation and permeabilisation solutions.

IQ Products has a wide range of antibodies for cancer research, which can be viewed here.

They also offer a variety of kits for flow cytometry in different research areas:

Perinatal kits

Fetal Cell Count Kit

The Fetal Cell Count Kit provides reproducible routine measurements in every situation where detection and quantification of foetal haemoglobin (HbF) in blood is needed. The assay is based on a combination of two antibodies: one is directed against HbF and the second is specific for carbonic anhydrase (CA), only present in adult red blood cells and, at very low detectable level, in late pregnancy stage (38+ weeks of gestation). This duplex assay allows for a lower rate of false positives associated with detecting adult F-cells using the Kleihauer-Betke acid-elution test or single HbF flow cytometry tests.

Features:

  • Quantitation of foetal-maternal haemorrhage (FMH)
  • Discrimination of foetal RBCs in maternal blood
  • Intracellular detection of HbF and CA

FMH QuikQuant

A Rapid assay for Foetomaternal Haemorrhage Quantification

The FMH QuikQuant Kit is a flow cytometric method for FMH detection and quantification. The assay uses a reagent containing a monoclonal antibody to Haemoglobin F and Propidium Iodide as a specific marker of nucleated cells. The method is a rapid streamlined technique requiring about 30 minutes to complete. With less than 15 minutes of hands-on time needed, it is more efficient to use than the Kleihauer-Betke assay, as well as more sensitive and precise.

Features

  • Detection of foetal haemoglobin (HbF) of as low as 0,06% foetal cells in maternal blood
  • Results in 1 hour (20 minutes hands-on-time) with two single centrifuge steps
  • IVD/CE

FETALtrol™

The FETALtrol kit provides control cells to validate the procedures for the detection of Foetomaternal Haemorrhage. You can choose from two kits, FH101 with 3 levels and two 2 mL vials for each level, or FH102 with three levels but just one 2 mL vial for each level.

  • Eliminates the need to acquire cord blood to make home brew controls, saving time precious to the laboratory workforce.
  • Three validated levels which correspond to clinical decision points for anti-D therapy.
  • 3 months total shelf life.
  • FDA cleared as a hematologic control for foetal red cell detection.
  • Registered as Medical Device for In Vitro Diagnostic Use (IVD/CE).

FETALtrol has a shelf life of three months from the date of manufacture, but you can sign up to our alert list to know when a new batch is ready. Please contact techsupport@caltagmedsystems.co.uk to join this alert list.

Kits for detection of HIT

HITAlert

HITAlert is the first functionality test for the diagnosis of HIT in heparin-treated patients using flow cytometry.

Heparin-induced thrombocytopenia (HIT) is an immune-mediated distinct syndrome in which laboratory detection of the pathogenic antibodies is diagnostically useful. The present functional flow cytometric assay determines the capacity of the patient's serum to activate platelets in presence of heparin. This functional assay reproduces the in vivo pathophysiology, and highly correlates with the clinical presentation of HIT. Indications for testing in patients exposed to heparin include the appearance of thrombocytopenia, or of thrombosis irrespective to platelet count.

Transplantation kits

CMV Brite™ Turbo Kit

The CMV Brite™ Turbo Kit is a complete kit for the rapid diagnosis of an active CMV infection in 2 hours.

Features

  • Detection of CMV pp65 positive PMNs by indirect immunofluorescence gives high sensitivity and easy reading of the results.
  • A cocktail of antibodies specific for pp65.
  • A complete kit containing all the reagents needed from cell preparation to immunofluorescence staining.
  • The number of CMV pp65 positive cells are counted per duplicate stain.
  • No evidence of cross reactivity between other viruses and CMV using the CMV antigenemia assay with the C10/C11 monoclonal antibody cocktail.
  • Control slides are included.
  • Completed within 2 hours of sample collection.
  • Registered as Medical Device for In Vitro Diagnostic Use (IVD/CE0344).
  • FDA cleared (USA) 510(k) #991650.

Applications

  • Bone marrow transplant recipients
  • Solid organ transplant patients
  • AIDS patients

CMV Brite™ Kit

CMV Brite™ Kit is a complete kit for the rapid diagnosis of an active CMV infection in 4 hours.

Features

  • Detection of CMV pp65 positive PMNs by indirect immunofluorescence gives high sensitivity and easy reading of the results.
  • A cocktail of antibodies specific for pp65.
  • A complete kit containing all the reagents needed from cell preparation to immunofluorescence staining.
  • The number of CMV pp65 positive cells are counted per duplicate stain.
  • No evidence of cross reactivity between other viruses and CMV using the CMV antigenemia assay with the C10/C11 monoclonal antibody cocktail.
  • Control slides are included.
  • Completed within 5 hours of sample collection.
  • The kit is available in a 100 tests version.
  • Registered as Medical Device for In Vitro Diagnostic Use (IVD/CE0344)
  • FDA cleared (USA) 510(k) #951550

Applications

  • Bone marrow transplant recipients
  • Solid organ transplant patients
  • HIV infected persons
  • AIDS patients

The following products related to CNV Brite and CMV Brite Turbo kits are also available:

Sepsis & Inflammation kits

Macro163™

With the Macro163™ kit, you can detect inflammation and bacterial sepsis using this soluble CD163 ELISA assay for measuring Macrophage and Monocyte Activation.

Features

  • Analyse Macro163 levels in serum and plasma
  • Complete ELISA kit
  • Based on the two most published soluble CD163 ELISA protocols
  • Assay completed within 4 hours
  • Use of fully characterized recombinant CD163 protein as standard
  • Standardized and quantitative
  • Only 2 uL of sample is needed
  • Pre-coated ELISA plates

Applications

  • Detection and monitoring of macrophage activation syndromes
  • Detection of myeloproliferative diseases and hemophagocytic syndrome
  • Risk-marker in low-grade inflammatory states
  • Prognostic marker in sepsis and liver-disease
  • Monitoring of sepsis combined with leukocyte CD163 and CD64 expression
  • Association with post-infectious recovery phase and declining inflammation

As IQ Product's distributor in the U.K., we are here to help with any queries related to their products. Do not hesitate to contact us for further information or to obtain a quote.

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