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Cancer - Jun 2018

CD138 detection you can trust

The respected anti-human CD138 (Syndecan-1) clone B-A38 developed by Diaclone is well documented in its use for plasma cell identification and multiple myeloma research. Whether you are looking for detection of membrane-bound CD138 via IHC or FCM, or looking to quantify soluble CD138 via ELISA, you can rely on Diaclone.
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Newsletter - Jun 2018

Welcome to the Caltag Medsystems Product Highlights.


 
Welcome to the Caltag Medsystems Product Highlights. Be sure to check out our brainteaser at the end of the newsletter!
 
1. 20µg of Primary Antibody for £20/€20
2. Next Day Delivery of Frozen Haematopoietic Cells
3. Extra Savings on Cloud Clone ELISA Kits
4. Exclusive Biochemicals and Rare Antibiotics
5. Which Cell System are you using in your Research?
6. Toxins - Tetanus, Cholera and other Highly Purified Bacterial Toxin       
7. Extracellular Vesicle Research Tools
8. Interested in Endotoxin-Free Antibody Purification?
9. Jellagen: Next Generation Collagen
10. Brainteaser: What am I?
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Exosomes - Jun 2018

Exosome Isolation from TransFix Stabilised Blood


Reduce the negative impact of platelet exosome release 
 
 Are you concerned that processing and storing your blood sample is inadvertently causing additional exosome release from platelets, and skewing your data?

The addition of TransFix® (a cell-stabilisation solution) at the point of blood collection may reduce the negative impact of platelet exosome release, giving better insights into events happening in vivo.


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Proteomics - Jun 2018

Remove Haemoglobin, Albumin and Lipids From Your Samples

Achieve higher data quality in proteomics analysis through Biotech Support Group’s new trial kits for: Lipid Removal & Clarification, Haemoglobin enrichment/removal and Albumin removal. These sample preparation products are well-used, highly published and share 4 common features and collective advantages:


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Blood - Jun 2018

Cord Blood Inventory from AllCells

Below is our current inventory of cord blood cells. AllCells offer umbilical cord stem cells, mononuclear cells and B and T cells. These products are available in fresh and frozen formats and are available from mixed cords or single cord donor. If you do not see your required product listed, please contact me as it could be produced as a custom product.
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Antibodies - May 2018

Biologically Active Antibodies for Investigating Cellular Assay Systems

Diaclone offers a broad range of biologically active, Azide Free antibodies suitable for Induction, Activation, Neutralisation and Inhibition Studies to investigate your cellular assay system:
 
Download Biologically Active Antibodies Flyer, detailing specific antibodies and their activity or View Biologically Active Antibodies on our website.
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Clinical Flow Cytometry - May 2018

Monitoring Multiple Myeloma?


 There are approximately 5,500 people diagnosed with Myeloma every year in the UK. It is the second most common form of blood cancer yet the causes of Myeloma are not fully understood. EuroFlow has partnered with Cytognos to design and validate a flow cytometry-based method for minimal residual disease (MRD) evaluation in Multiple Myeloma (MM).
 
Our MM MRD Panel (CE/IVD) is:
  • Fast/ time saving
  • Ultrasensitive
  • Simple to use
  • Convenient
  • Cost effective
And provides an accurate assessment of MM MRD.
 
Try it yourself with our MM MRD Sample Kit available now, and if you have the Infinicyt v.2.0 advanced software you can compare your results with various healthy bone marrow samples through the EuroFlow Databases.
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ProSci - Apr 2018

Celebrate 20 Years of Antibody Expertise with ProSci!

In celebration of ProSci's 20th Anniversary of making high quality antibodies, we are providing 20µg vials of primary antibodies, for just £20/€20. Perfect if you are looking to evaluate a new primary antibody!

Quote “20for20” on your order to qualify.

Find Your New Antibody

So, how does it work?

Choose any of the ProSci antibodies on the list and then place your order like normal with Caltag Medsystems. Be sure to quote “20for20” to qualify!


BioVision - Apr 2018

Methionine, Cysteine, Homocysteine and Taurine Assay Kits

BioVision is excited to be the first company in the market to offer assay kits for the detection of all four sulphur-containing amino acids:

Methionine (Met) - the starting amino acid in the biosynthesis of every protein;

Cysteine - plays a vital role in protein folding due to its ability to form disulphide bonds;

Homocysteine - functions as the precursor of cysteine and methionine.

Taurine - may act as antioxidant, neurotransmitter and membrane stabiliser.

Purchase any 2 or more products across the entire BioVision range and save money. Visit our Special Offers page for details. Explore our catalogue of products and take advantage of these products!




Newsletter - Apr 2018

Life Science Solutions: Cell Culture Reagents, GFP-Labelled Angiogenesis Assay, Cell Expansion Service, Human Tissue Sourcing, Proteomic and NGS Sample Prep, Compound Encapulation, PCA-Free Hydrox

Welcome to the Caltag Medsystems Product Highlights. Be sure to check out our brainteaser at the end of the newsletter!

  • ScienCells’ Reagents
  • Measure Angiogenesis in Real Time Using GFP-Labelled HUVECs
  • Cell Expansion Service
  • Do you Require Human Tissue Samples for Research?
  • Proteomic Sample Preparation Kits
  • Prepare your NGS Library in just 2.5 hours
  • Encapsulate Compounds and Obtain Nanovesicles
  • Perchlorate-Free Measurement of Hydroxyproline and Total Collagen
  • The Only P62 Phospho-Specific ELISA Kit on the Market
  • Brain Teaser – Bird Brain

Tetramers, Flow Cytometry - Apr 2018

Superior Detection and Screening of Immuno-Oncology Targets

The use of a patient's own immune system to combat cancer has become an increasingly popular area of research and drug development. However, a greater understanding is needed to learn how cancer cells bypass immune checkpoints and how scientists can use the immune system for cancer immunotherapy.

MBL International offers over 2000 MHC Tetramers and Monomers for antigen-specific t-cell detection, including QuickSwitch™ Tetramers for high throughput immunogenic peptide discovery and validation.



Europe, Newsletter - Mar 2018

Life Science Solutions: Angiogenesis, Cell Expansion, Tissue Samples, Animal Cells, Molecular Biology Reagents and More!

Welcome to the Caltag Medsystems Product Highlights! We aim to bring you a selection of new products, special offers, and exciting news from our portfolio, with a signature quiz to test your grey-matter.

  • Measure Angiogenesis in real time using GFP labelled HUVECs
  • Cell Expansion Service
  • Do you Require Human Tissue Samples for Research?
  • Animal Cells
  • Proteomic Sample Preparation Kits
  • Save On Top Selling ELISA Kits
  • Small Molecules for your Apoptosis and Epigentics Research
  • Bulk pricing for inhibitors, antibody purification reagents, detergents and more
  • Brain Teaser

Cell Culture - Mar 2018

Cells & Tissues: Blood and Collagen Products, Transfection and Cell Culture Reagents, Cell Expansion Services and More!

Welcome to the Caltag Medsystems Product Highlights! We aim to bring you a selection of new products, special offers, and exciting news from our portfolio, with a signature quiz to test your grey-matter.

Blood Products collected with Donor Specifications
Jellagen: Next Generation Collagen
High Efficient Transfection into Neuronal Cells – Act now for 20% off
ScienCells’ Reagents
Measure Angiogenesis in real time using GFP labelled HUVECs
Cell Expansion Service
Do you Require Human Tissue Samples for Research?
Frozen Skin Inventory
Brain Teaser: Heard But Never Seen

- Mar 2018

Skin Research Solutions: 3D Culture, Cells, Homeostasis Media, Biopsy Maintenance Media & Increase Isolation Efficiency

1. Chemically Defined Co-Culture, 3D-Culture and Homeostasis Media

2. Chemically Defined Biopsy Maintenance Medium

3. Double Your Isolation Efficiency with IsoBoost

Toxins - Mar 2018

Tetanus, Cholera and Other Highly Purified Bacterial Toxins


Toxins have been the basis for many vaccines, and List Labs products have been instrumental in supporting vaccine development. Toxins extracted and purified from bacteria are available for use in a variety of clinical research applications including: Botulinum, Staphylococcal, Shiga, Clostridial, Tetanus, Pertussis, Difficile, Anthrax, Diphtheria and Cholera. For information about purchasing these products please email us or call 01280 827460


Drug Discovery - Mar 2018

Drug Discovery Solutions: Liquid Biopsy CTC Isolation Devices, Quanitfy CYPs, HepaRG Cell Line, Tissue Samples, PD-1 Antibodies

Welcome to the Caltag Medsystems Product Highlights! Make sure to try our quiz at the end of the newsletter!

Liquid Biopsy: CTC Isolation Devices
Prepare your NGS Library in just 2.5 hours
Do you require Human Tissue Samples for Research?
Silensomes: Quantifying the Contribution of CYP Enzymes in Drug Metabolism
Hepatocyte Cell Line; HepaRG
The only anti-PD-1 and PD-L1 Single Domain Antibodies on the Market
Toxins: Tetanus, Cholera and Other Highly Purified Bacterial Toxins
Brainteaser: What am I?

Transfection - Mar 2018

Highly Efficient Transfection into Neuronal Cells from Oz Biosciences

NeuroMag - a transfection reagent specifically developed to transfect primary neurons and neural cells. 

Until 7 May 2018, enjoy a 20% discount on all NeuroMag products from Oz Biosciences using the promotional code: Neuro2018.

NeuroMag Transfection Reagent is a Magnetofection™ transfection reagent dedicated to neurons.

General - Mar 2018

Analyse Phosphorylated p62 with Phospho-specific ELISA kits

The Only Phosphorylated p62 ELISA Kits on the Market

p62 contains multiple phosphorylation sites which regulate biological defence mechanisms such as selective autophagy and the Keap1-Nrf2 system. Failure of the p62 pathway is associated with various diseases such as cancer and many neurodegenerative diseases so phospho-p62 is a hot topic of research.

Caltag Medsystems provide the only commercial Phospho-p62 Ser349 and Ser403 ELISA kits on the market, manufactured by MBL International.

Next Generation Sequencing - Mar 2018

Prepare your NGS Library in just 2.5 hours

Paragon Genomics develops kits and panels to amplify target regions of DNA using multiplex PCR for Next-Generation Sequencing (amplicon sequencing) target enrichment and library preparation on Illumina Sequencers.

Cell Culture - Feb 2018

World's First Pseudogene Transcription Analysis qPCR Kits

160 different Cell Pellets Now Available

Cells | Stem Cells | Media | Reagents | Growth Factors | Assay Kits | Gene Analysis
 Pseudogene Transcription Analysis
World's First Pseudogene Transcription Analysis qPCR Kits
Pseudogenes have garnered substantial interest in current cell biology and pathology studies, as their transcription has been shown to be much more common and functionally important than previously thought. Furthermore, pseudogenes, due to the high sequence similarity to their related functional genes, may skew the qPCR analysis data of the latter no matter using fluorescent dye (such as SYBR® Green) or probes, as their primers and probes may bind to pseudogene cDNA with no or little discrimination. Therefore, accurate transcription analysis of pseudogenes themselves, as well as the precise separation of it from the functional genes, are critical for research.

To better assist you in analyzing pseudogene transcription and its influence on functional gene expression, ScienCell has developed the world's first pseudogene transcription analysis qPCR kits. Our kits guarantee that each primer set only amplifies the designated gene or pseudogene without cross-amplification. For more information on psuedogenes and how they may affect your functional gene analysis, please read our blog post, Hidden Treasure in "Junk DNA"... Learn more

Currently available kits:

Product Code Gene Code Product Description
SC-GK806 GQP-FER1L4 GeneQuery™ Human PTEN-FER1L4 Pseudogene Transcription Analysis qPCR Kit
SC-GK807 GQP-FER1L4-B GeneQuery™ Human OTOF-FER1L4 Pseudogene Transcription Analysis qPCR Kit
SC-GK808 GQP-KRASP1 GeneQuery™ Human KRAS-KRASP1 Pseudogene Transcription Analysis qPCR Kit
SC-GK809 GQP-MT1DP GeneQuery™ Human MT1A-MT1DP Pseudogene Transcription Analysis qPCR Kit
SC-GK810 GQP-MYLKP1 GeneQuery™ Human MYLK-MYLKP1 Pseudogene Transcription Analysis qPCR Kit
SC-GK812 GQH-SUMO1P3 GeneQuery™ Human SUMO1-SUMO1P3 Pseudogene Transcription Analysis qPCR Kit
SC-GK813 GQP-TMPOP2 GeneQuery™ Human TMPO-TMPOP2 Pseudogene Transcription Analysis qPCR Kit
SC-GK815 GQP-ZNF300P1 GeneQuery™ Human ZNF300-ZNF300P1 Pseudogene Transcription Analysis qPCR Kit
 

View All Available Pseudogene Kits

ELISpot - Feb 2018

Monitor T-Cell Response to IFN-Gamma with the Diaclone ELISpot Assay

Highly Cited IFN-Gamma ELISpot Assays

The Enzyme Linked Immunospot (ELISpot) Assay is an ideal tool to evaluate the efficacy of novel cancer immunotherapies and cancer vaccines. The Diaclone IFN-Gamma ELISpot Assay is highly cited in over 70 publications, and offers a sensitive, specific and robust assay to assess the frequency of IFN-Gamma reactive T-Cells.

This assay has been successfully utilised in two recent studies published in Clinical Cancer Research by Dosse et al. and Godet et al. (download the application note "Monitoring the T-Cell Response to Tumor Antigens" for details). 

Diaclone offer IFN-Gamma ELISpot Kits with pre-coated plates, and ELISpot Sets available with or without non-coated plates. To find out more...


Bone Marrow - Feb 2018

Fresh and Frozen Bone Marrow Options

Did you know that AllCells are able to provide whole bone marrow aspirate and bone marrow cells collected from healthy individuals?  Up to 100ml of bone marrow can be collected per donor with sodium heparin used as a standard anti-coagulant (other anti-coagulants available as a custom request). AllCells have compared and studied multiple aspiration techniques to develop an IRB approved protocol that minimises the amount of peripheral blood in the bone marrow.

Exosomes - Feb 2018

The Problem with Ultracentrifugation for Exosome Isolation

Ultracentrifugation is regarded as the gold standard method for exosome isolation. The ultracentrifugation process is time consuming and may introduce protein and nucleic acid contamination. Pre-clearing samples by one or more low speed centrifugation steps will deplete the cells, platelets, and large apoptotic bodies. Larger extracellular vesicles can be pelleted at forces between 10000-20000 x g. Smaller extracellular vesicles can be pelleted at higher speeds, ranging from 100000-200000 x g. Depending on the protocol, it can take up to 24 hours to isolate exosomes by ultracentrifugation. It is impossible to achieve absolute separation due to potential contamination of proteins and nucleic acids...

ExoCap™ Streptavidin Kit - Faster, Easier and Customisable
The ExoCap™ Streptavidin Kit protocol is very easy and simple to follow. Researchers can isolate and enrich for exosomes of interest by coupling biotinylated molecules to the magnetic Streptavidin beads. There is no need for pre-treatment of samples because there is a direct incubation of sample with the Streptavidin magnetic beads. The magnetic Streptavidin beads coupled with biotinylated antibodies will selectively capture exosomes of interest. During the wash step the captured exosomes on the magnetic bead are retained, while any contaminants are removed, resulting in high purity exosomes that can be used for downstream analyses in as little as 4 hours.

Angiogenesis, Cell Culture, France - Feb 2018

Nouveau: Mesure de l’angiogénèse en temps réel en utilisant HUVEC GFP labellisé

Le GFP V2a Kit ™ - Vasculogénèse à l'Angiogénèse, est un modèle de co-culture de cellules primaires humaines validées, in vitro, de l'angiogenèse. Il permet la mesure dynamique de toutes les phases du processus angiogénique.

Small Molecules - Feb 2018

2017 Top 100 Small Molecules for your Apoptosis and Epigentics Research

Meet APExBIO –  An apoptosis and epigentics company. 

APExBIO provides a broad range of Apoptosis, Epigenetics, and Cancer Biology research reagents.  Plus custom services including peptide synthesis, antibody production and assay development.

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