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General - Sep 2019

Special offer! 20μg of primary antibody for £20/€20

ProSci has more than 20 years experience in making high quality antibodies, we are providing 20µg vials of primary antibodies, for just £20/€20 which is up to 70% discount. Perfect if you are looking to evaluate a new primary antibody!
 
But be quick - this promotion expires on the 30th November 2019.
 
Quote “20for20” on your order to qualify.
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Newsletter - Aug 2019

Drug Discovery Solutions: Cell Expansion Service, ELISA Kits for Your Research, CTC Isolation Devices, Traceable Cell Culture Media and More

1. Evaluating The Biological Activity of a Cancer Vaccine
2. Fluorescent Tools For Drug Discovery
3. Cell Expansion Service
4. Do you Require Human Tissue Samples for Research?
5. Liquid Biopsy: CTC Isolation Devices
6. Clinically Relevant Mesenchymal Stem Cell Populations for Research
7. The Importance of Fully Traceable Cell Culture Media
8. ELISA Kits for Your Research
9. Brainteaser: 4 Vowels 1 Word
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Nervous System - Aug 2019

Conducting neural differentiation research?

Why use GeneQuery™ qPCR arrays?

 
✔ Gene selection is based on extensive literature research by Ph.D. scientist team
✔ All known transcript variants of target gene are recognized
✔ Primers are verified with over 10 types of normal human primary cells to assure universal specificity and biological relevance
✔ Performance guaranteed with high efficiency and reproducibility; free of non-specific amplification
✔ Customizable with no extra charge
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Adipogen - Aug 2019

eTOPIX_New Biologically Active Small Molecules

Unique Biologically Active Small Molecules
Lantibiotics, Necroptosis Inhibitors,
Metastasis Inhibitors, Metabokines,
Antidiabetic & Immunosuppressive Agents,
Lipid A & MPLA Sterile Solutions
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Cell Culture - Aug 2019

Save Time Sourcing Hepatocytes

Sourcing Hepatocytes Has Never Been Easier...
 
Fresh Hepatocytes
 
Cryopreserved Hepatocytes
 
Hepatocyte Cell Line: HepaRG
 
Animal Hepatocytes
 
We’ve tried to make our product range as comprehensive as possible, but please let us know if you are having trouble sourcing a product or human/animal tissue and we will help you find it.
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Prosci - Aug 2019

Single domain antibodies?

Single domain is at the forefront of antibody research, due to its small size (a mere 15 kDa), they are adept at reaching epitopes inaccessible to conventional antibodies. Learn more about the advantages of single domain antibodies and their development.
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General - Aug 2019

ALK Gene Fusion Detection Probe

Wuhan HealthCare manufactures innovative solutions for cancer and personalised medicine that answer questions related to the earlier diagnostic, prognosis and therapy selection. This has significantly changed the way patients are treated. Our product lines consist of DNA Fluorescence In Situ Hybridisation (FISH) probes for cancer clinical diagnosis, research and pharmacogenetics real-time PCR kits for drug sensitivity.
Human ALK gene fusion detection probe is specifically used for non-small cell lung cancer (NSCLC).
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MBL - Aug 2019

The Use of Immunotherapy in Treating HHV-6 Infection

Human herpesvirus 6 (HHV-6) is a virus that exists as 2 species, HHV-6A and HHV-6B. HHV-6B, the more widespread species, is a pathogen infecting more than 90% of individuals world-wide during childhood and then establishing a latent and lifelong infection. HHV-6B reactivation occurs in its immunocompromised host (e.g. patients receiving allogeneic hematopoietic stem cell or solid-organ transplantation and AIDS patients) and causes severe complications.
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Newsletter - Aug 2019

Life Science Solutions: Immunometabolism Brochure, Single Domain Antibodies, Protein Enrichment and Removal, Antibiotics and Mycotoxin Special Offer, and More

1. New Immunometabolism Brochure
2. For Adhesion Molecule Antibodies… Stick with us!
3. Single Domain Antibodies?
4. Cell Expansion Service
5. Antibiotics and Mycotoxin Special Offer
6. Exploring the Digestive Tract?
7. Remove Haemoglobin, Albumin, Lipids and Enrich Your Samples
8. ELISA Kits for Your Research
9. Measure Angiogenesis in real time using GFP labelled HUVECs
10. Greater Value for Flow Cytometry Antibodies 
11. Brainteaser: A Mother Has Three Children
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Flow Cytometry - Aug 2019

Haematology Malignancies Screening Tubes

Haematological malignancies (cancers of the blood, bone marrow and lymph nodes) represents a significant area of clinical and research activity. Cytognos have collaborated with EuroFlow to develop panels used for screening haematological malignancies through flow cytometry, including:
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Biovision - Aug 2019

T-Gel-Agarose: For purification of Immunoglobulins (IgG, IgE, IgM, IgA, IgY)


i-Bind™ T-Gel-Agarose

 
Thiophilic Adsorption Chromatography (TAC) is a group-specific, salt-dependent purification technique with distinct adsorption affinity towards immunoglobulins and α2-macroglobulins. TAC has proven to be an easy and economical method for purification of many types of proteins, especially immunoglobulins under universal and mild conditions (neutral pH). BioVision’s Hi-Bind™ T-Gel Agarose beads provides up to 30 mg of protein per ml settled beads capacity and allow rapid purification of any type of immunoglobulins from serum, ascites, tissue culture including IgG, IgE, IgM, IgA, IgY and Fab fragments.
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Cytomark - Jul 2019

Innovative Applications of TransFix

TransFix is designed for stabilisation of peripheral blood and cerebrospinal fluid to enumerate lymphocyte subpopulations by flow cytometry. However, researchers have developed many new and innovative uses of TransFix.
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Cell Culture - Jul 2019

Skin: Fresh & Frozen Samples, Isolated Cells and Subcellular Fractions

Caltag Medsystems supply both fresh and frozen human skin for use in different applications including: drug permeation, skin irritation, toxicology, and metabolism, as well as primary cell isolation.
In addition, we provide a wide range of skin cells: fibroblasts, keratinocytes, melanocytes and skin subcellular fractions.
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Cell Culture - Jul 2019

3D Blood-Brain-Barrier Spheroid Model

Mimicking the blood-brain barrier (BBB) in vitro is a challenging task, but is critical for understanding the central nervous system (CNS) diseases and drug permeability testing.
 
ScienCell has developed both the Ready-To-Use and All-Inclusive 3D Blood Brain Barrier (BBB) Spheroid kits. See below for more information.

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Antibodies - Jul 2019

Discover Elabscience Antibody Sampler Kits

Elabscience Antibody Sampler Kits are designed to provide scientific researchers with high-quality and cost-efficient specific antibodies required to detect multiple target proteins in cellular responses or signalling pathways. Their antibody sampler kits cover a wide range of research areas including:
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Clinical - Jul 2019

Clinical Solutions and Equipment: BCP ALL MRD Kit, Skin Blistering kits, IVD Antibodies, Brainteasers and More

Welcome to the Caltag Medsystems Clinical Product Highlights. Be sure to check out our brainteaser at the end of the newsletter!

 
1. B-cell Precursor (BCP) Acute Lymphoblastic Leukaemia Detection Kit
2. Differential Diagnosis of Pemphigus and Bullous Pemphigoid
3. Leucocytes Stabilisation in CSF Samples
4. FETALtrol™: Tri-level Controls for FMH
5. IVD Flow Cytometry Antibodies
6. Brain Teaser: Backwards Cheese
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Antibiotics - Jul 2019

Antibiotics and Mycotoxin Special Offer

Antibiotics can be classified based on their mechanism of action, chemical structure, mode of production (fermentation, synthetic or semisynthetic), producing organisms (bacterial, fungi [incl. mycotoxins]) or spectrum of activity.
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Antibodies - Jul 2019

Highly Specific Validated Monoclonal Antibodies

NSJ Bioreagents provide a wide selection of Human Protein Microarray Validated Antibodies. The specificity of these antibodies to their intended targets has been validated by the HuProt(TM) human proteome microarray, containing more than 19,000 full-length human proteins, resulting in extremely specific antibodies with high consistency from batch to batch and a long stability.
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Immunology - Jul 2019

Immunology Research Portfolio

Caltag Medsystems has access to over 10,000 reagents for immunological research including; ELISA kits, antibodies, proteins, tetramers and more. 
 
Immune Tissue - All immune cells originate in the bone marrow, deriving from haematopoietic stem cells. We are capable of sourcing fresh whole bone marrow, diseased whole bone marrow, bone marrow isolated cells and bone marrow mesenchymal cells.
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Cell Culture - Jul 2019

Cells & Tissues: MSCs, Naturally Better Cell Culture, Freezing Medium, Cell Expansion Service, Brainteasers and More

1. Clinically Relevant Mesenchymal Stem Cell Populations for Research
2. Naturally Better Cell Culture
3. Animal Component Free Freezing Medium
4. Highly Efficient Transfection into Neuronal Cells 
5. Cell Expansion Service
6. Do you Require Human Tissue Samples for Research?
7. Measure Angiogenesis in real time using GFP labelled HUVECs
8. Media For Intestinal Organoid Cell Culture
9. Brainteaser: Happens Only in the Middle of Each Month
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Biovision - Jul 2019

Lipid Second Messengers... With Primary Roles

A Second messenger is a molecule that is released intracellularly in response to cell’s exposure to exogenous signaling molecules —also known as first messengers. Second messengers play vital roles in cell proliferation, differentiation, migration, and apoptosis. The list of second messengers includes cyclic AMP, calcium, cGMP, Nitric Oxide, hydrogen sulfide, diacylglycerol (DAG), etc. On the other hand, phospholipids act directly on second messenger activity/bioproduction: Lysophosphatidylcholine activates numerous secondary messengers – including PKC, protein tyrosine kinase, and calcium; while phosphatidic acid and phosphatidylcholine are precursors of DAG. BioVision offers a vast, yet increasing number of products for the quantitation of second messengers, phospholipids and enzymatic activities. Our assay kits are simple to perform, reproducible and validated with relevant biological samples.
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Cell Culture - Jun 2019

Mesenchymal Stem Cells & CELLvo™ Matrix

Don’t Compromise Your Work 

Your work is important. Trust CELLvo™. The CELLvo™ Matrix is the only substrate available that closely mimics the full physical, structural, and biochemical microenvironment found in the human body. Together with our CELLvo™ Cells, cell culture artifacts are eliminated allowing the cells to respond to YOU.
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Flow Cytometry - Jun 2019

EuroFlow Antibodies and Reagents

Cytognos provide flow cytometry reagents and antibodies for cell analysis, research and diagnostic purposes. This includes a range of Euroflow validated antibodies such as: CD8, CD56, Kappa, Lambda and CD81, in addition to other single colour and combination antibodies.

The Euroflow consortium is made up of various influential research groups whose aim is the development and standardisation of fast, accurate, and highly sensitive flow cytometric tests for diagnosis and prognostic (sub)classification of haematological malignancies as well as for evaluation of treatment effectiveness during follow-up.
In collaboration with EuroFlow, Cytognos have developed various panels for the Haematological malignancies:
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Immunology - Jun 2019

eTOPIX_New Gasdermin Research Tools for Pyroptosis Research

Gasdermin D (mouse) ELISA Kit 
 
The Gasdermin D (mouse) ELISA Kit is a sandwich ELISA for quantitative determination of mouse Gasdermin D in cell culture supernatants and in cell extracts. This ELISA is specific for the measurement of natural and recombinant mouse Gasdermin D (full-length and C-terminus cleaved fragment). It does not detect human Gasdermin D

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Cytomark - Jun 2019

Protocol Available - Extend the Integrity of Cerebrospinal Fluid Leucocytes

Why Stabilise Cerebrospinal Fluid with TransFix? 

Within Cerebrospinal Fluid (CSF) specimens, the qualitative and quantitative characterisation of infiltrated leucocytes via flow cytometry is an important tool for identification of various hematologic diseases [1, 2]. However, the number of leucocytes present in CSF is often very low and degrade quickly. Therefore, assessment of these cells is reliant upon urgent analysis which is not always possible.
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