anti-GITR (mouse) mAb (MGIT 02)

AdipoGen Life Sciences
Product Code: AG-20A-0007
Product Group: Primary Antibodies

CodeSizePrice
AG-20A-0007-C100100 ug£162.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2aκ
Antibody Clonality: Monoclonal
Antibody Clone: MGIT 02
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
Shipping:
Blue Ice
Storage:
-20°C

Images

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FACS: GITR-transfected HEK 293 cells stained significantly using anti-GITR (mouse), mAb (MGIT 02) (Prod. No. AG-20A-0007).

FACS: GITR-transfected HEK 293 cells stained significantly using anti-GITR (mouse), mAb (MGIT 02) (Prod. No. AG-20A-0007).

Further Information

Alternate Names/Synonyms:
Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant mouse GITR.
Long Description:
Monoclonal Antibody. Recognizes mouse GITR. Does not cross-react with human GITR. Isotype: Rat IgG2akappa. Clone: MGIT 02. Applications: ELISA, FACS. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.
NCBI, Uniprot Number:
O35714
Package Type:
Plastic Vial
Product Description:
GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.
Specificity:
Recognizes mouse GITR. Does not cross-react with human GITR.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells: H.H. Shin, et al.; Bone 36, 832 (2005)