Annexin V (human) (rec.)

Annexin A5; Endonexin II; Lipocortin V; Placental Anticoagulant Protein I; Calphobindin I; Vascular Anticoagulant-alpha

1mg/ml after reconstitution

32160000

solid

Lyophilized. In PBS.

Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.Repeated freeze/thaw cycles (>3) may result in an adverse effect on the activity.

Protein. Recombinant human annexin V fused to a GST-tag. Source: E. coli. Lyophilized. In PBS, pH 7.4. Binds to phosphatidylserine (PS). Purity: >95% (SDS-PAGE). Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

~52kDa (SDS-PAGE)

P08758

Plastic Vial

Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

>95% (SDS-PAGE)

Recombinant human annexin V fused to a GST-tag.

E. coli

Binds to phosphatidylserine (PS).

GST

Non-hazardous

Other Proteins

12352202

Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.