Annexin V (human) (rec.) (ATTO 488)

AdipoGen Life Sciences
Product Code: AG-40B-0005TD
Product Group: Recombinant Proteins

CodeSizePrice
AG-40B-0005TD-T100100 tests£120.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: E.coli
Regulatory Status: RUO
Target Species: Human
Shipping:
Blue Ice
Storage:
4°C

Further Information

Alternate Names/Synonyms:
Annexin A5; Endonexin II; Lipocortin V; Placental Anticoagulant Protein I; Calphobindin I; Vascular Anticoagulant-alpha
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In PBS, pH 7.4, containing 0.02% sodium azide.
Handling Advice:
Do not freeze.Protect from light.
Labels - Conjugates:
ATTO 488
Long Description:
Protein. Recombinant human annexin V fused to a GST-tag. Source: E. coli. Liquid. In PBS, pH 7.4, containing 0.02% sodium azide. Binds to phosphatidylserine (PS). Purity: >95% (SDS-PAGE). Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Molecular Weight:
~52kDa (SDS-PAGE)
NCBI, Uniprot Number:
P08758
Other data:
Application: This protein can be used for the detection of apoptotic cells by flow cytometry or immunofluorescence (100 tests/0.5ml). Note: A Flow Cytometry Protocol is available at www.adipogen.com.
Package Type:
Plastic Vial
Product Description:
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Purity:
>95% (SDS-PAGE)
Sequence:
Recombinant human annexin V fused to a GST-tag.
Source / Host:
E. coli
Specificity:
Binds to phosphatidylserine (PS).
TAGs:
GST
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.