(-)-Indolactam V
| Code | Size | Price |
|---|
| AG-CR1-0041-C300 | 300 ug | £180.00 |
Quantity:
| AG-CR1-0041-M001 | 1 mg | £350.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
4°C
Documents
Further Information
Appearance:
Off-white to light yellow solid.
CAS:
90365-57-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1
InChiKey:
LUZOFMGZMUZSSK-LRDDRELGSA-N
Long Description:
Chemical. CAS: 90365-57-4. Formula: C17H23N3O2. MW: 301.4. Tumor promoter. Protein kinase C (PKC) inducer. Mitogenesis activator. Differentiation inducer.
MDL:
MFCD00151197
Molecular Formula:
C17H23N3O2
Molecular Weight:
301.4
Other data:
May contain traces of (+)-Indolactam V.
Package Type:
Vial
Precautions:
P261, P271, P280, P312
Product Description:
Tumor promoter [1]. Protein kinase C (PKC) inducer [2]. Mitogenesis activator [3]. Differentiation inducer [4].
Purity:
>95%
Signal word:
Warning
SMILES:
CC(C)[C@@H]1N(C)C2=CC=CC3=C2C(C[C@@H](CO)NC1=O)=CN3
Solubility Chemicals:
Soluble in DMSO or 100% ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin: H. Fujiki, et al.; Gann 75, 866 (1984) | (-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells: J. Heikkil? & K. Akerman; BBRC 162, 1207 (1989) | (-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways: N. Papadogiannakis; Cell. Immunol. 162, 288 (1995) | A small molecule that directs differentiation of human ESCs into the pancreatic lineage: S. Chen, et al.; Nat. Chem. Biol. 5, 258 (2009) | Angiopoietins stimulate pancreatic islet development from stem cells: S.S. Karanth, et al.; Nature Sci. Rep. 11, 13558 (2021)
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