EGFR Soluble (human) (rec.)

AdipoGen Life Sciences
Product Code: AG-40T-0041
Product Group: Recombinant Proteins

CodeSizePrice
AG-40T-0041-C02525 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Shipping:
Blue Ice
Storage:
+4°C

Further Information

Alternate Names/Synonyms:
Epidermal Growth Factor Receptor; ERBB1; HER1
EClass:
32160000
Form (Short):
solid
Formulation:
Lyophilized.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Source: Sf9 cells. Lyophilized. Purity: >90% (SDS-PAGE). EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
Molecular Weight:
~85kDa
NCBI, Uniprot Number:
P00533
Package Type:
Plastic Vial
Product Description:
EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
Purity:
>90% (SDS-PAGE)
Sequence:
Human EGFR (629aa) is fused at the C-terminus to a Strep-tag.
Source / Host:
Sf9 cells
TAGs:
Strep
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.