Angiopoietin-2 (mouse) (rec.)
| Code | Size | Price |
|---|
| AG-40B-0131-C010 | 10 ug | £170.00 |
Quantity:
| AG-40B-0131-3010 | 3 x 10 ug | £330.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Clonality: Enzyme
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Shipping:
Blue Ice
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Ang-2; Ang2; Angpt2; Agpt2
Concentration:
0.1 mg /ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.05EU/µg purified protein (LAL test).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS with trehalose and Brij35.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.05EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS with trehalose and Brij35. Binds to the human and mouse Tie-2 receptor. Purity: >95% (SDS-PAGE). Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
Molecular Weight:
~70kDa (SDS-PAGE)
NCBI, Uniprot Number:
O35608
Package Type:
Plastic Vial
Product Description:
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
Purity:
>95% (SDS-PAGE)
Sequence:
Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag.
Source / Host:
HEK 293 cells
Specificity:
Binds to the human and mouse Tie-2 receptor.
TAGs:
FLAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.