3-Hydroxykynurenine Transaminase (Anopheles gambiae) (rec.)
| Code | Size | Price |
|---|
| AG-40T-0100-C050 | 50 ug | £357.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Clonality: Enzyme
Regulatory Status: RUO
Shipping:
Dry Ice
Storage:
-80°C
Documents
Further Information
Alternate Names/Synonyms:
3-HKT; EC 2.6.1
Biological Activity:
Specific activity towards D,L-3HK: 33 µmol/min per mg. Primarily catalyses the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA).
Concentration:
0.5mg/ml (Lot specific)
EClass:
32160000
Endotoxin:
N/A
Form (Short):
liquid
Formulation:
Liquid. In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40µM pyridoxal 5'-phosphate (PLP).
Handling Advice:
After opening, prepare aliquots and store at -80°C.Avoid freeze/thaw cycles.
Long Description:
Protein. Full-length 3-HKT (Anopheles gambiae) is untagged. Source: E. coli. Endotoxin content: N/A. Liquid. In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40µM pyridoxal 5'-phosphate (PLP). Purity: >99% (SDS-PAGE). The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.
Molecular Weight:
~44.3kDa
NCBI, Uniprot Number:
Q7PRG3
Package Type:
Plastic Vial
Product Description:
The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.
Purity:
>99% (SDS-PAGE)
Sequence:
Full-length 3-HKT (Anopheles gambiae) is untagged.
Source / Host:
E. coli
TAGs:
no TAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Enzymes
UNSPSC Number:
12352204
Use & Stability:
Stable for at least 6 months after receipt when stored at -80°C.
References
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase: F. Rossi, et al.; FEBS J. 272, 5653 (2005) | Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase: F. Rossi, et al.; PNAS 103, 5711 (2006)