ABCC1 monoclonal antibody
| Code | Size | Price |
|---|
| MAB5158-1mL | 1 mL | £933.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Clonality: Monoclonal
Antibody Clone: QCRL-4
Regulatory Status: RUO
Documents
Further Information
Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
ABC29|ABCC|DKFZp686N04233|DKFZp781G125|GS-X|MRP|MRP1
Gene Description:
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Gene ID:
4363
Gene Name:
ABCC1
Immunogen:
Native human small cell lung cancer cell line H69AR.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native ABCC1.
Recommend Dilutions:
Flow Cytometry (1:20-1:40)
Dot Blot (1:10000)
The optimal working dilution should be determined by the end user.
Dot Blot (1:10000)
The optimal working dilution should be determined by the end user.
Specificity:
QCRL-4 reacts with a conformation-dependent internal epitope of MRP1, a 190 KDa trans-membrane phosphoglycoprotein overexpressed in various human multidrug resistant tumor cell lines. QCRL-4 inhibits the ATP-dependent transport activity of MRP1 in inside-out membrane vesicles and its epitope has been localized to the second nucleotide binding domain of MRP1 between amino acids 1294 and 1531. QCRL-4 does not cross-react with human MDR1 and MDR3 gene products.
Storage Buffer:
In PBS (0.7% BSA, 0.09% sodium azide)