FGF-1 (mouse) (rec.)

AdipoGen Life Sciences
Product Code: AG-40B-0148
Product Group: Recombinant Proteins

CodeSizePrice
AG-40B-0148-C01010 ug£90.00
Quantity:
AG-40B-0148-30103 x 10 ug£170.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: E.coli
Regulatory Status: RUO
Target Species: Mouse
Shipping:
Blue Ice
Storage:
-20°C

Further Information

Alternate Names/Synonyms:
Fibroblast Growth Factor 1; Acidic Fibroblast Growth Factor; Endothelial Cell Growth Factor; ECGF; Heparin-binding Growth Factor 1; HBGF-1
Concentration:
0.1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.01EU/µg purified protein (LAL test).
Form (Short):
liquid
Formulation:
Lyophilized. In PBS containing 0.2 mM DTT.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Mouse FGF-1 (aa 16-155) is untagged. Source: E. coli. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. In PBS containing 0.2 mM DTT. Purity: >95% (SDS-PAGE). Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
Molecular Weight:
~16kDa
NCBI, Uniprot Number:
P61148
Package Type:
Plastic Vial
Product Description:
Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
Purity:
>95% (SDS-PAGE)
Sequence:
Mouse FGF-1 (aa 16-155) is untagged.
Source / Host:
E. coli
TAGs:
no TAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

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