anti-APRIL (mouse) mAb (rec.) (blocking) (Apry-1-3)

A Proliferation Inducing Ligand; TNFSF13; CD256; TALL-2

1mg/ml

32160000

<0.01EU/µg purified protein (LAL-test; Lonza)

liquid

Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.

Mouse APRIL (aa 98-232).

Recombinant Antibody. Recognizes mouse APRIL. Does not recognize mouse BAFF. Species cross-reactivity: Mouse. Clone: Apry-1-3. Isotype: Human IgG1lambda. Applications: ELISA, FUNC (Blocking), IP. Host: Purified from HEK 293 cell culture supernatant. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-3) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.

Q9D777

APRIL (mouse) monoclonal antibody (recombinant) (blocking) (APRY-1-3) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG1 Fc domain.

Plastic Vial

APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-3) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.

>95% (SDS-PAGE)

Produced without the use of animals. Purified from HEK 293 cell culture supernatant.

Recognizes mouse APRIL. Does not recognize mouse BAFF.

Non-hazardous

Primary Antibodies

12352203

Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.