Cyclosporin C
Product Code: AG-CN2-0443
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0443-M001 | 1 mg | £55.00 |
Quantity:
| AG-CN2-0443-M005 | 5 mg | £190.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Thr2-Cyclosporine; CsC
Appearance:
White solid.
CAS:
59787-61-0
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07,GHS08
Handling Advice:
Keep cool and dry.Protect from light.
Hazards:
H302, H350, H360
InChi:
InChI=1S/C62H111N11O13/c1-25-26-27-39(14)52(76)51-56(80)66-49(42(17)74)60(84)67(18)32-47(75)68(19)43(28-33(2)3)55(79)65-48(37(10)11)61(85)69(20)44(29-34(4)5)54(78)63-40(15)53(77)64-41(16)57(81)70(21)45(30-35(6)7)58(82)71(22)46(31-36(8)9)59(83)72(23)50(38(12)13)62(86)73(51)24/h25-26,33-46,48-52,74,76H,27-32H2,1-24H3,(H,63,78)(H,64,77)(H,65,79)(H,66,80)/b26-25-/t39-,40+,41-,42-,43+,44+,45+,46+,48+,49-,50+,51+,52-/m1/s1
InChiKey:
JTOKYIBTLUQVQV-PODIXWLNSA-N
Long Description:
Chemical. CAS: 59787-61-0. Formula: C62H111N11O13. MW: 1218.6. Isolated from Fusarium solani. Immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Antifungal. Antitumor.
MDL:
MFCD06410945
Molecular Formula:
C62H111N11O13
Molecular Weight:
1218.6
Package Type:
Vial
Precautions:
P301, P312, P308, P313, P330
Product Description:
Immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Antifungal. Antitumor.
Purity:
>95% (HPLC)
Signal word:
Danger
SMILES:
[H][C@@]1([C@H](O)[C@H](C)CC=CC)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)C(NC1=O)[C@@H](C)O)C(C)C
Solubility Chemicals:
Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water.
Source / Host:
Isolated from Fusarium solani.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.
References
The structure of cyclosporin c: R. Traber, et al.; Helv. Chim. Acta 60, 1247 (1977) | Cyclosporins: immunosuppressive agents with antitumor activity: W. Kreis & A. Soricelli; Experientia 35, 1506 (1979) | Monitoring cyclosporine by HPLC with cyclosporin C as internal standard: P.M. Jones & K. Brune; Clin. Chem. 39, 168 (1993) | Cyclosporin C is the main antifungal compound produced by Acremonium luzulae: M. Moussaif, et al.; Appl. Environ. Microbiol. 63, 1739 (1997)
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