COX-2 Inhibitor 8c

AdipoGen Life Sciences
Product Code: AG-CR1-3606

CodeSizePrice
AG-CR1-3606-M0011 mg£170.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
Compound 8c; 4-[(1E)-2-(Thienyl)ethenyl]-benzenesulfonamide
Appearance:
White solid.
CAS:
1259295-44-7
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.
Hazards:
H302, H319, H335
InChi:
InChI=1S/C12H11NO2S2/c13-17(14,15)12-7-4-10(5-8-12)3-6-11-2-1-9-16-11/h1-9H,(H2,13,14,15)/b6-3-
InChiKey:
OZEBJQJPQRQDDH-UTCJRWHESA-N
Long Description:
Chemical. CAS: 1259295-44-7. Formula: C12H11NO2S2. MW: 265.4. Potent cyclooxygenase-2 (COX-2) inhibitor. Inhibits inflammatory prostaglandin E2 (PGE2) production.
MDL:
N/A
Molecular Formula:
C12H11NO2S2
Molecular Weight:
265.4
Package Type:
Vial
Precautions:
P261, P264, P270, P271, P280, P301, P312
Product Description:
Potent cyclooxygenase-2 (COX-2) inhibitor. Inhibits inflammatory prostaglandin E2 (PGE2) production.
Purity:
>98% (NMR)
Signal Word:
Warning
SMILES:
NS(=O)(=O)C1=CC=C(C=CC2=CC=CS2)C=C1
Solubility Chemicals:
Soluble in DMSO or methanol. Insoluble in water.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Styrylheterocycles as a novel class inhibitor of cyclooxygenase-2-mediated prostaglandin E(2) production: S.K. Lee, et al.; Bioorg. Med. Chem. Lett. 14, 2105 (2004) | Sulfonamide derivatives of styrylheterocycles as a potent inhibitor of COX-2-mediated prostaglandin E2 production: C. Lim, et al.; Bioorg. Med. Chem. Lett. 20, 6938 (2010)