BMP-5 Recombinant Protein

ProSci
Product Code: PSI-40-541
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-40-541-0.002mg0.002mg£300.00
Quantity:
PSI-40-541-0.01mg0.01mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized BMP-5 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing

Documents

Further Information

Additional Names:
Bone morphogenetic protein 5, BMP-5
Background:
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
Biological Activity:
Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 μg/mL. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
653
NCBI Official Name:
bone morphogenetic protein 5
NCBI Official Symbol:
BMP5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_066551.1
Protein GI Number:
10835091
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P22003