ICAM-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-238-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-238-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized ICAM-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted ICAM-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
BB2, CD54, P3.58, Intercellular adhesion molecule 1, Major group rhinovirus receptor, ICAM-1
Background:
ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of approximately 72.0-80.0 kDa by SDS-PAGE analysis under reducing conditions.
Biological Activity:
ICAM - 1 supported the adhesion of more than 50% PMA - stimulated HSB2 cells to plates coated at 25 ng/mL ICAM - 1 concentration
NCBI Gene ID #:
3383
NCBI Official Name:
intercellular adhesion molecule 1
NCBI Official Symbol:
ICAM1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000192.2
Protein GI Number:
167466198
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P05362