IL-13 Recombinant Protein

ProSci
Product Code: PSI-40-258
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-40-258-0.002mg0.002mg£300.00
Quantity:
PSI-40-258-0.01mg0.01mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-13 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-13 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos

Documents

Further Information

Additional Names:
P600, IL-13, NC30, Interleukin-13
Background:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant human IL-13 is a 12.5 kDa protein consisting of 114 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
NCBI Gene ID #:
3596
NCBI Official Name:
interleukin 13
NCBI Official Symbol:
IL13
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_002179.2
Protein GI Number:
26787978
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P35225