IL-19 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-264-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-264-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-19 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-19 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
MDA1, NG.1, ZMDA1, IL-10C, Interleukin-19, Melanoma differentiation-associated protein-like protein, IL-19
Background:
IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant Human IL-19 is a 35.8 kDa homodimer of two 154 amino acid chains. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.
Biological Activity:
Biological activity was determined by its ability to activate STAT following receptor - ligand interaction.
NCBI Gene ID #:
29949
NCBI Official Name:
interleukin 19
NCBI Official Symbol:
IL19
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_037503.2
Protein GI Number:
30795208
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9UHD0