IL-3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-245-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-245-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
Documents
Further Information
Additional Names:
IL-3, MCGF, MULTI-CSF, Interleukin-3, Hematopoietic growth factor, IL-3
Background:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is ≤ 0.1 ng/mL, corresponding to a specific activity of ≥ 1 x 107 units/mg.
NCBI Gene ID #:
3562
NCBI Official Name:
interleukin 3 (colony-stimulating factor, multiple)
NCBI Official Symbol:
IL3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000579.2
Protein GI Number:
28416915
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P08700