4-1BB Ligand Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-303-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-303-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized 4-1BB Ligand recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted 4-1BB Ligand is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any
Documents
Further Information
Additional Names:
CD137L, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4-1BBL
Background:
4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of IL - 8 production by human PBMC. The ED50 for this effect is 5 - 10 ng/mL. Please Note: Results may vary with PBMC donors.
NCBI Gene ID #:
8744
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 9
NCBI Official Symbol:
TNFSF9
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003802.1
Protein GI Number:
4507609
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P41273