Myostatin Propeptide Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-210-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-210-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Myostatin Propeptide recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Myostatin Propeptide is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°
Documents
Further Information
Additional Names:
GDF8, MSLHP, GDF8, Myostatin, GDF-8
Background:
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
Biological Activity:
Biological activity was determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC - 11 cells. The expected ED50is 0.01 - 0.04 μg/mL in the presence of 50 ng/mL Myostatin.
NCBI Gene ID #:
2660
NCBI Official Name:
myostatin
NCBI Official Symbol:
MSTN
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_005250.1
Protein GI Number:
4885259
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O14793