Resistin Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-325-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-325-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Resistin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein,
Documents
Further Information
Additional Names:
ADSF, RSTN, XCP1, FIZZ3, RETN1, HXCP1, UNQ407/PRO1199, Resistin, Adipose tissue-specific secretory factor, ADSF
Background:
Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond.
Background References:
- Ort, T. et al. Endocrinology; 46(5):2200 - 9
Biological Activity:
Biological activity was determined by its ability to stimulate lipolysis in cultured human adipocytes.
NCBI Gene ID #:
56729
NCBI Official Name:
resistin
NCBI Official Symbol:
RETN
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001180303.1
Protein GI Number:
301129180
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9HD89