CDMP-2 Recombinant Protein

ProSci
Product Code: PSI-40-202
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-40-202-0.01mg0.01mg£300.00
Quantity:
PSI-40-202-0.05mg0.05mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized CDMP-2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CDMP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp

Documents

Further Information

Additional Names:
KFM, KFS, KFS1, KFSL, SGM1, BMP13, CDMP2, LCA17, MCOP4, SCDO4, MCOPCB6, GDF16GDF-6
Background:
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Biological Activity:
The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC - 5 chondrogenic cells in the range of 2.0 - .0 μg/mL.
NCBI Gene ID #:
392255
NCBI Official Name:
growth differentiation factor 6
NCBI Official Symbol:
GDF6
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001001557.1
Protein GI Number:
48475062
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q6KF10