BMP-4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-549-0.01mg | 0.01mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized BMP-4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BMP-4 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4
Background:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. ProSci?s E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Biological Activity:
Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/mL. Endotoxin level is less than 0.1 ng per μg of BMP-4 (1EU/μg).
NCBI Gene ID #:
652
NCBI Official Name:
bone morphogenetic protein 4
NCBI Official Symbol:
BMP4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001193.2
Protein GI Number:
157276593
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P12644