NT-3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-565-0.01mg | 0.01mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized NT-3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NT-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing N
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Further Information
Additional Names:
NT3, HDNF, NGF2, NT-3, NGF-2, Neurotrophin-3
Background:
NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical.
Biological Activity:
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/mL. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
4908
NCBI Official Name:
neurotrophin 3
NCBI Official Symbol:
NTF3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001096124.1
Protein GI Number:
156630995
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P20783