NT-4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-566-0.01mg | 0.01mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized NT-4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NT-4 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing N
Documents
Further Information
Additional Names:
NT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5, Neurotrophin-4, Neurotrophin-5
Background:
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).Manufactured using all non-animal reagents.
Biological Activity:
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/mL. Endotoxin level is less than 0.1 ng per μg of NT-4 (1EU/μg).
NCBI Gene ID #:
4909
NCBI Official Name:
neurotrophin 4
NCBI Official Symbol:
NTF4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_006170.1
Protein GI Number:
5453808
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P34130