Fetuin A Recombinant Protein

ProSci
Product Code: PSI-40-554
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-40-554-0.01mg0.01mg£300.00
Quantity:
PSI-40-554-0.05mg0.05mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Fetuin A recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Fetuin A stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, ex

Documents

Further Information

Additional Names:
AHS, A2HS, HSGA, FETUA, PRO2743, Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin
Background:
Fetuin A/AHSG is a human plasma glycoprotein belonging to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuin A/AHSG is a major serum protein component that exerts various calcium dependent physiological activities, and can mediate growth signaling in certain tumor cells. It also can act as a natural antagonist against specific TGF-β and BMP signaling proteins, Recombinant human Fetuin-A is a heterodimeric protein containing a 282 amino acid A chain and a 27 amino acid B chain. Due to glycosylation, recombinant Fetuin-A migrates at an apparent molecular weight of 45 - 55 kDa by SDS-PAGE run under non-reducing conditions.
Biological Activity:
Biological activity was determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is = 100nM. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
197
NCBI Official Name:
alpha-2-HS-glycoprotein
NCBI Official Symbol:
AHSG
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001613.2
Protein GI Number:
156523970
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P02765