IL-10 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-417-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-417-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
CSIF, Il-10, Interleukin-10, Cytokine synthesis inhibitory factor, IL-10
Background:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.
Biological Activity:
Murine IL - 10 is fully biologically active as measured by the dose - dependent co - stimulation (with IL - 4) of the proliferation of murine MC/9 cells. The ED50 was found to be < 2 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
NCBI Gene ID #:
16153
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
Il10
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_034678.1
Protein GI Number:
6754318
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P18893