IL-10 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-471-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-471-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Rat
Storage:
The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
IL10X, Il-10, Interleukin-10, Cytokine synthesis inhibitory factor, IL-10
Background:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent inhibition of antigen - specific T cell proliferation is less than 10 ng/mL.
NCBI Gene ID #:
25325
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
Il10
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_036986.2
Protein GI Number:
148747382
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P29456