IgG4 Fc Region Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-419-0.2mg | 0.2mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).
Background References:
- Frangione B., et al., 1969, Nature 221:145-148.
- Kristiansen T.Z., et al., 2004, Mol. Cell. Proteomics 3:715-728.
- Chen R., et al., 2009, J. Proteome Res. 8:651-661.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
NCBI Gene ID #:
3503
NCBI Official Name:
immunoglobulin heavy constant gamma 4 (G4m marker)
NCBI Official Symbol:
IGHG4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
25.8 kDa
Protein Accession #:
P01861
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P01861