WSX 1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-455-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL27RA, CRL1, TCCR, WSX1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin-27 receptor subunit alpha (IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
Background References:
- Sprecher C.A., et al., 1998, Biochem. Biophys. Res. Commun. 246:82-90.
- Chen Q., et al., 2000, Nature 407:916-920.
- Pflanz S., et al., 2004, J. Immunol. 172:2225-2231.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
9466
NCBI Official Name:
interleukin 27 receptor, alpha
NCBI Official Symbol:
IL27RA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
79 kDa
Protein Accession #:
AAH28003
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q6UWB1