IFNAR 1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-405-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IFNAR1, IFNAR, CRF2-1, IFN-R-1, IFNAR-1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interferon alpha/beta receptor 1 (IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
Background References:
- Colamonici O., et al., 1994, Mol. Cell. Biol. 14:8133-8142.
- Li X., et al., 1997, Mol. Cell. Biol. 17:2048-2056.
- Russell-Harde D., et al., 1999, Biochem. Biophys. Res. Commun. 255:539-544.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
3454
NCBI Official Name:
interferon (alpha, beta and omega) receptor 1
NCBI Official Symbol:
IFNAR1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
73.8 kDa
Protein Accession #:
NP_000620
Purity:
85% (rh IFNAR1 /IFNAR Fc Chimera) and 13% (Human IgG1 Fc fragment) as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P17181